The pharmacokinetics of once-daily oral 400 mg ofloxacin in patients with peritonitis complicating continuous ambulatory peritoneal dialysis

Journal of Antimicrobial Chemotherapy

Volumn 39, Issue 6, 1997, Pages 829-831

  McMullin, C M ^a   Brown, N M ^a   Brown, I M ^a   Tomson, C R V ^b   White, L O ^a   Reeves, D S ^a   MacGown, A P ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b SOUTHMEAD HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; OFLOXACIN; PERITONEAL DIALYSIS FLUID;

ADULT; AGED; ARTICLE; BACTERIAL PERITONITIS; CHRONIC KIDNEY FAILURE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTINUOUS AMBULATORY PERITONEAL DIALYSIS; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; FEMALE; HUMAN; MALE; ORAL DRUG ADMINISTRATION; PERITONITIS;

AGED; ANTI-INFECTIVE AGENTS; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; MALE; MIDDLE AGED; OFLOXACIN; PERITONEAL DIALYSIS; PERITONITIS;

EID: 0030742477     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/39.6.829     Document Type: Article

References (9)

1. Williams, J. D. & Coles, G. A. (1992). CARD peritonitis. International Journal of Antimicrobial Agents 1, 165-74.
2. Bennett-Jones, D. N., Russell, G. I. & Barrett, A. (1990). A comparison between oral ciprofloxacin and intra-peritoneal vancomycin and gentamicin in the treatment of CARD peritonitis. Journal of Antimicrobial Chemotherapy 26, Suppl. F, 73-6.
3. Gruneberg, R. N., Felmingham, D., O'Hare, M. D., Robbins, M. J., Perry, K., Wall, R. A. et al. (1988). The comparative in-vitro activity of ofloxacin. Journal of Antimicrobial Chemotherapy 22, Suppl. C, 9-19.
4. Lode, H., Hoffken, G., Prinzing, C., Glatzel, P., Wiley, R., Olschewski, P. et al. (1987). Comparative pharmacokinetics of new quinolones. Drugs 34, Suppl. 1, 21-5.
5. Höffler, D. & Koeppe, P. (1987). Pharmacokinetics of ofloxacin in healthy subjects and patients with impaired renal function. Drugs 34, Suppl. 1, 51-5.
6. White, L. O., MacGowan, A. P., Lovering, A. M., Reeves, D. S. & MacKay, I. G. (1987). A preliminary report on the pharmacokinetics of ofloxacin, desmethyl ofloxacin and ofloxacin N-oxide in patients with chronic renal failure. Drugs 34, Suppl. 1, 56-61.
7. Kampf, D., Borner, K. & Pustelnik, A. (1990). Pharmacokinetics of ofloxacin and adequacy of maintenance dose for patients on haemodialysis. Journal of Antimicrobial Chemotherapy 26, Suppl. D, 61-8.
8. Gokal, R., Jakubowski, C., King, J., Hunt, L., Bogle, S., Baillod, R. et al. (1987). Outcome in patients on continuous ambulatory peritoneal dialysis and haemodialysis: 4-year analysis of a prospective multicentre study. Lancet ii, 1105-9.
9. Körner, R. J., McMullin, C. M., Bowker, K. A., White, L. O., Holt, H. A., Reeves, D. S. et al. (1993). The serum concentrations of desmethyl ofloxacin and ofloxacin N-oxide in seriously ill patients and their possible contributions to the antibacterial activity of ofloxacin. Journal of Antimicrobial Chemotherapy 34, 300-3.