Validation of p53 immunohistochemistry as a prognostic factor in breast cancer in clinical practice

Archives of Pathology and Laboratory Medicine

Volumn 126, Issue 4, 2002, Pages 456-458

  Bartley, Angela N ^a   Ross, Dennis W ^a  

^a FORSYTH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN ANTIBODY; PROTEIN P53;

ARTICLE; BREAST CANCER; CLINICAL PRACTICE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INVASIVE CARCINOMA; MAJOR CLINICAL STUDY; PROGNOSIS; TUMOR SUPPRESSOR GENE;

ADULT; BIOPSY; BREAST NEOPLASMS; CARCINOMA IN SITU; CARCINOMA, INTRADUCTAL, NONINFILTRATING; FEMALE; GENES, P53; HOSPITALS, COMMUNITY; HUMANS; IMMUNOENZYME TECHNIQUES; MUTATION; PROGNOSIS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0036213804     PISSN: 00039985     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Prognostic factors in breast cancer: College of American Pathologists Consensus Statement 1999
2. A prospective trial of Midwest breast cancer patients: A p53 gene mutation is the most important predictor of adverse outcome
3. Mutation detection by highly sensitive methods indicates that p53 gene mutations in breast cancer have important prognostic value
4. Accumulation of p53 tumor suppressor gene protein: An independent marker of prognosis in breast cancers
5. Prognostic and predictive factors in breast cancer by immunohistochemical analysis
6. The prognostic value of p53 and c-erb B-2 immunostaining is overrated for patients with lymph node negative breast carcinoma: A multivariate analysis of prognostic factors in 613 patients with a follow-up of 14-30 years
7. Expression of p53 protein has no independent prognostic value in breast cancer
8. Correlation between the expression of apoptosis-related bcl-2 and p53 oncoproteins and the carcinogenesis and progression of breast carcinomas
9. Prognostic significance of the co-expression of p53 and c-erbB-2 proteins in breast cancer
10. Prognostic value of p53 protein expression in breast carcinomas
11. p53 quantitative immunohistochemical analysis in breast carcinomas
12. p53 as an independent prognostic marker in lymph node-negative breast cancer patients
13. Association of overexpression of tumor suppressor protein p53 with rapid cell proliferation and poor prognosis in node-negative breast cancer patients
14. Immunohistochemical expression of p53 protein in invasive breast carcinoma: Clinicopathologic correlations
15. Immunohistochemical co-expression of c-erbb-2/Neu oncoprotein, altered tumour suppressor (p53) protein, EGF-R and EMA in histological subtypes of infiltrating duct carcinoma of the breast
16. p53 determination alongside classical prognostic factors in node-negative breast cancer: An evaluation at more than 10-year follow-up