Oxidative modification of NK30424A and B enhance inhibitory effect on lipopolysaccharide-induced tumour necrosis factor-α promoter activity

Journal of Antibiotics

Volumn 55, Issue 3, 2002, Pages 337-340

  Takayasu, Yoshiyuki ^a   Tsuchiya, Kouichi ^a   Sukenaga, Yoshikazu ^a  

^a NIPPON KAYAKU CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPOLYSACCHARIDE; NK 30424 A; NK 30424 AS 1; NK 30424 AS 2; NK 30424 B; NK 30424 BS 1; NK 30424 BS 2; POLYPEPTIDE ANTIBIOTIC AGENT; SULFOXIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

CHEMICAL MODIFICATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG OXIDATION; DRUG STRUCTURE; MOLECULAR WEIGHT; NONHUMAN; NOTE; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

EID: 0036213349     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.55.337     Document Type: Note

References (3)

1. NK30424A and B, novel inhibitors of lipopolysaccharide-induced tumour necrosis factor alpha production, produced by Streptomyces sp. NA30424
2. κB-Type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumour necrosis factor-α gene in primary macrophages
3. Aberrant rel/nfkb genes and activity in human cancer