Perforin- and Fas-dependent mechanisms of natural killer cell-mediated rejection of incompatible bone marrow cell grafts

European Journal of Immunology

Volumn 32, Issue 3, 2002, Pages 793-799

  Taylor, Mesha Austin ^a   Ward, Brant ^a   Schatzle, John D ^a   Bennett, Michael ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cytotoxicity; NK cell; Transplantation

Indexed keywords

FAS ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PERFORIN; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ANTIBODY;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL DEATH; CELL STRAIN; CONTROLLED STUDY; EXOCYTOSIS; GRAFT REJECTION; KNOCKOUT MOUSE; MOUSE; NATURAL KILLER CELL; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; TARGET CELL; TUMOR CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD95; APOPTOSIS; BONE MARROW TRANSPLANTATION; CROSSES, GENETIC; CYTOPLASMIC GRANULES; CYTOTOXICITY, IMMUNOLOGIC; EXOCYTOSIS; FAS LIGAND PROTEIN; GRAFT REJECTION; H-2 ANTIGENS; HISTOCOMPATIBILITY; HOUSING, ANIMAL; KILLER CELLS, NATURAL; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; PORE FORMING CYTOTOXIC PROTEINS; RADIATION CHIMERA; RECEPTORS, TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036210735     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200203)32:3<793::AID-IMMU793>3.0.CO;2-M     Document Type: Article

References (26)

1. Biology of natural killer cells
2. Perforin and serine esterase gene expression in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A
3. Duel mechanisms of apoptosis induction by cytotoxic lymphocytes
4. Expression of perforin and serine esterases by human gamma/delta T cells
5. Cytotoxicity with target DNA breakdown by rat basophilic leukemia cells expressing both cytolysin and granzyme A
6. The control of hematopoiesis and leukemia: From basic biology to the clinic
7. Role of TNF in lymphocyte-mediated cytotoxicity
8. Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells
9. Compromised anti-tumor responses in tumor necrosis factor-alpha knockout mice
10. Perforin, Fas ligand, and tumor necrosis factor are the major toxic molecules used by lymphokine-activated killer cells
11. Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice
12. Perforin- and Fas-medated cytotoxic pathways are not required for allogeneic resistance to marrow grafts in mice
13. Cytokine and cytotoxic pathways of NK cell rejection of class I deficient bone marrow grafts: Influence of mouse colony environment
14. Functional defects of NK cells treated with chloroquine mimic the lytic defects observed in perforin deficient mice
15. Inhibition of the death receptor pathway by cFLIP confers partial engraftment of MHC class I-deficient stem cells and reduces tumor clearance in perforin-deficient mice
16. Genetic control of bone marrow transplantation in irradiated mice: Classification of mouse strains according to their responsiveness to bone marrow allografts and xenografts
17. Effects of breeding environments on generation and activation of autoreactive B-1 cells in anti-red blood cell autoantibody transgenic mice
18. Metalloproteinase-mediated release of human Fas ligand
19. Regulation of cell surfaceAPO-1/Fas (CD95) ligand expression by metalloproteinases
20. Effects of inhibitors of inflammatory mediators and cytokines on eosinophil and neutrophil accumulation induced by Mycobacterium bovis bacillus Calmette-Guerin in mouse pleurisy
21. Natural killer cells ands their role in graft rejection
22. Peculiar immunobiology of bone marrow allografts. I. Graft rejection by heavily irradiated "responder" mice
23. Differential down-regulation of CD95 and CD95L in chronically HIV-infected cells of monocytic or lymphocyte origin
24. Transforming growth factor beta 1 inhibits Fas ligand expression and subsequent activation-induced cell death in T cells via down-regulation of c-Myc
25. Graft-versus-host reactions in mice. I. Kinetic and immunogenetics studies of alloantigen-sensitive units of lymphoid tissue
26. + T cells