Inhibitory effects of prostaglandin A1 on apoptosis of rat cardiac microvascular endothelial cells was mediated by NF-κB

Acta Pharmacologica Sinica

Volumn 23, Issue 4, 2002, Pages 331-335

  He, Jing Kang ^a   Gu, Zhen Lun ^a   Fan, Pan Sheng ^a  

^a MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

Author keywords

Apoptosis; bcl 2 genes; Cultured cells; in situ nick end labeling; NF kappa B; Prostaglandins A; Vascular endothelium

Indexed keywords

DNA FRAGMENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROSTAGLANDIN A1; PROTEIN BAX; PROTEIN BCL 2; BAX PROTEIN, RAT; MESSENGER RNA; ONCOPROTEIN; PROSTAGLANDIN A;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ELECTROPHORESIS; ENDOTHELIUM CELL; HYPOXIA; MICROVASCULATURE; NICK END LABELING; NONHUMAN; NORTHERN BLOTTING; PROTEIN EXPRESSION; RAT; REOXYGENATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CAPILLARY; CELL CULTURE; CELL HYPOXIA; CORONARY BLOOD VESSEL; CYTOLOGY; DRUG EFFECT; GENETICS; METABOLISM; VASCULAR ENDOTHELIUM; WISTAR RAT;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CAPILLARIES; CELL HYPOXIA; CELLS, CULTURED; CORONARY VESSELS; ENDOTHELIUM, VASCULAR; NF-KAPPA B; PROSTAGLANDINS A; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; RNA, MESSENGER;

EID: 0036207454     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Treating myocardial ischemia-reperfusion injury by targeting endothelial cells transcription
2. Inhibition of NF-κB activation by pyrrolidine dithiocarbamate prevents in vivo expression of proinflammatory genes
3. Peripheral blood mononuclear cells induce programmed cell death in human endothelial cells and may prevent repair: Role of cytokines
4. Inhibition of nuclear factor κB by prostaglandin Al: An effect associated with heat shock transcription factor activation
5. Isolation and characterization of human and rat cardiac microvascular endothelial cells
6. Effects of TNF, IL-1 and IL-2 on cardiac microvascular endothelial cells and neutrophil adhesiveness
7. Effects of hypoxia and reoxygen on brain microvascular endothelial cells expressing ICAM-1
8. Detection of DNA fragmentation in apoptosis: Application of in situ nicked translation to cell culture systems and tissue sections
9. A study of in situ detection of cell apoptosis by fluorescence and colorimetric TUNEL
10. Rapid detection of octamer binding proteins with 'miniextracts', prepared from a small number of cells
11. Effects of c-myc expression on cell cycle progression
12. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
13. Induction of the stress response with prostaglandin A1 increases I-κBα gene expression
14. Nuclear factor κB nuclear translocation upregulates c-Myc and p53 expression during NMDA receptor-mediated apoptosis in rat striaturn
15. Inhibition of TNF-induced apoptosis by NF-κB
16. NF-κB to the rescue: RELs, apoptosis and cellular transformation