Optimization of glycerol feeding for clavulanic acid production by streptomyces clavuligerus with glycerol feeding

Biotechnology Letters

Volumn 24, Issue 6, 2002, Pages 455-458

  Chen, Kuo Cheng ^a   Lin, Yun Huin ^a   Tsai, Cheng Min ^a   Hsieh, Chen Hao ^a   Houng, Jer Yiing ^b  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b I SHOU UNIVERSITY   (Taiwan)

Author keywords

Clavulanic acid; Feeding; Glycerol; Streptomyces clavuligerus

Indexed keywords

CLAVULANIC ACID; GLYCEROL;

ANTIBIOTIC BIOSYNTHESIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEGRADATION; DRUG SYNTHESIS; FED BATCH FERMENTATION; INTERMETHOD COMPARISON; NONHUMAN; PRODUCTIVITY; STREPTOMYCES CLAVULIGERUS;

STREPTOMYCES; STREPTOMYCES CLAVULIGERUS;

EID: 0036204270     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1014553109425     Document Type: Article

References (8)

1. Catabolite regulation of cephalosporin production in Streptomyces clavuligerus
2. Naturally-occurring β-lactamase inhibitors with antibacterial activity
3. 13C-labelled precursors
4. Assay of amoxicillin and clavulanic acid, the components of Augmentin, in biological fluids with high-performance liquid chromatography
5. Growth limiting substrate affects antibiotic production and associated metabolic flues in Streptomyces clavuligerus
6. Clavulanic acid, a β-lactamase inhibitor: Biosynthesis and molecular genetics
7. Simultaneous production and decomposition of clavulanic acid during Streptormyces clavuligerus cultivations
8. Dissociation of cephamycin and clavulanic acid biosynthesis in Streptomyces clavuligerus