Persistence of tumor DNA in plasma of breast cancer patients after mastectomy

Annals of Surgical Oncology

Volumn 9, Issue 1, 2002, Pages 71-76

  Silva, Jose M ^a   Garcia, Jose M ^a   Dominguez, Gemma ^a   Silva, Javier ^a   Miralles, Celia ^a   Cantos, Blanca ^a   Coca, Santiago ^b   Provencio, Mariano ^a   España, Pilar ^a   Bonilla, Felix ^a  

^a HOSPITAL UNIVERSITARIO PUERTA DE HIERRO   (Spain)

^b Hospital Militar del Aire   (Spain)

Author keywords

Circulating DNA; Genetic markers; Mammary malignancies; Poor prognosis; Postmastectomy

Indexed keywords

DNA; PROTEIN P53;

ARTICLE; BREAST CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; DNA EXTRACTION; DNA METHYLATION; GENETIC MARKER; HUMAN; LYMPH NODE METASTASIS; MASTECTOMY; MICROSATELLITE MARKER; MONONUCLEAR CELL; POINT MUTATION; PROGNOSIS;

BREAST NEOPLASMS; DNA METHYLATION; DNA, NEOPLASM; FEMALE; GENES, P16; GENES, P53; GENETIC MARKERS; HUMANS; MASTECTOMY; MICROSATELLITE REPEATS; MUTATION; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; POLYMERASE CHAIN REACTION; POSTOPERATIVE PERIOD; PREOPERATIVE CARE; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 0036202754     PISSN: 10689265     EISSN: None     Source Type: Journal    
DOI: 10.1245/aso.2002.9.1.71     Document Type: Article

References (35)

1. Cancer statistics
2. Tumor suppressor genes
3. The p53 gene in breast cancer: Prognostic value of complementary DNA sequencing versus immunohistochemistry
4. p53 mutations in BRCA 1-associated familial breast cancer
5. Microsatellite instabilities at five chromosomes in primary breast tumors
6. Microsatellite instability in sporadic human breast cancer
7. Consortium study on 1280 breast carcinomas: Allelic loss on chromosome 17 target subregions associated with family history and clinical parameters
8. Loss of heterozygosity in normal tissue adjacent to breast carcinomas
9. Loss of heterozygosity in bRCA1 and BRCA2 markers and high-grade malignancy in breast cancer
10. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
11. Detection of oncogene mutations in sputum precedes diagnosis of lung cancer
12. Identification of p53 gene mutations in bladder cancers and urine samples
13. Detection of point mutations in the K-ras oncogene at codon 12 in pure pancreatic juice for diagnosis of pancreatic carcinoma
14. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors
15. Detection of c-erbB-2 gene amplification in nipple discharge by means of polymerase chain reaction
16. Microsatellite alterations in plasma DNA of small cell lung cancer patients
17. Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients
18. Presence of tumor DNA in plasma of breast cancer patients: Clinicopathological correlations
19. Detecting tumor-related alterations in plasma or serum DNA of patients diagnosed with breast cancer
20. Microsatellite abnormalities in plasma of patients with breast carcinoma: Concordance with the primary tumour
21. Microsatellite alterations in plasma DNA of primary breast cancer patients
22. K-ras mutations are found in DNA extracted from the plasma of patients with colorectal cancer
23. Molecular detection of genetic alterations in serum of colorectal cancer patients
24. K-ras mutations in DNA extracted from the plasma of patients with pancreatic carcinoma: Diagnostic utility and prognostic significance
25. Free DNA in the serum of cancer patients and the effect of therapy
26. High-density genetic map of the BRCA 1 region of chromosome 17q12-q21
27. Detection of bladder cancer recurrence by microsatellite analysis of urine
28. High frequency of allelic imbalance at chromosome region 16q22-23 in human breast cancer: Correlation with high PgR and low S phase
29. Chromosome 9p allelic loss and p16/CDKN2 in breast cancer and evidence of p16 inactivation in immortal breast epithelial cells
30. Optimization of nonradioisotopic single strand conformation polymorphism analysis with a conventional minislab gel electrophoresis apparatus
31. Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction
32. TP53 gene mutations in plasma DNA of cancer patients
33. Methylation specific PCR a novel PCR assay for methylation status of CpG islands
34. Quantitative analysis of cell-free Epstein-Barr virus DNA in plasma of patients with nasopharyngeal carcinomas
35. Rapid clearance of fetal DNA from maternal plasma