NF-κB activation by tumor necrosis factor and interleukin-1

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 64, Issue , 1999, Pages 473-483

  Cao, Z ^a   Tanaka, M ^a   Regnier, C ^a   Rothe, M ^a   Yamit Hezi, A ^a   Woronicz, J D ^a   Fuentes, M E ^b   Durnin, M H ^b   Dalrymple, S A ^b   Goeddel, D V ^a  

^a AMGEN INC   (United States)

^b ROCHE BIOSCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR; ACUTE PHASE PROTEIN; CRADD PROTEIN; I KAPPA B; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 2; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 3; MYELOID DIFFERENTIATION FACTOR 88; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED DEATH DOMAIN PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

COMPLEX FORMATION; CONFERENCE PAPER; EMBRYO DEVELOPMENT; HUMAN; IMMUNOREGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ARTICLE; AUTOPHOSPHORYLATION; CYTOKINE RELEASE; DEATH DOMAIN; FIBROBLAST; GENE OVEREXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; IMMUNOPRECIPITATION; NEGATIVE FEEDBACK; POINT MUTATION; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION; UBIQUITINATION;

EID: 0033513187     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.1999.64.473     Document Type: Conference Paper

References (39)

1. Abbondanzo S.J., Cullinan E.B., McIntyre K., Labow M.A., and Stewart C.L. 1996. Reproduction in mice lacking a functional type 1 IL-1 receptor. Endocrinology 137: 3598.
2. Acton R.D., Dahlberg P.S., Uknis M.E., Klaerner H.G., Fink G.S., Norman J.G., and Dunn D.L. 1996. Differential sensitivity to Escherichia coli infection in mice lacking tumor necrosis factor p55 or interleukin-1 p80 receptors. Arch. Surg. 131: 1216.
3. Adachi O., Kawai T., Takeda K., Matsumoto M., Tsutsui H., Sakagami M., Nakanishi K., and Akira S. 1998. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18mediated function. Immunity 9: 143.
4. Ashkenazi A. and Dixit V.M. 1998. Death receptors: Signaling and modulation. Science 281: 1305.
5. Baeuerle P.A. and Baltimore D. 1996. NF-κB: Ten years after. Cell 87: 13.
6. Baldwin A.S., Jr. 1996. The NF-κB and I κB proteins: New discoveries and insights. Annu. Rev. Immunol. 14: 649.
7. Barnes P.J. and Karin M. 1997. Nuclear factor-κB: A pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 336: 1066.
8. Beg A.A. and Baltimore D. 1996. An essential role for NF-κB in preventing TNF-α-induced cell death. Science 274: 782.
9. Belvin M.P., Jin Y., and Anderson K.V. 1995. Cactus protein degradation mediates Drosophila dorsal-ventral signaling. Genes Dev. 9: 783.
10. Boldin M.P., Varfolomeev E.E., Pancer Z., Men I.L., Camonis J.H., and Wallach D. 1995. A novel protein that interacts with the death domain of Fas/APOl contains a sequence motif related to the death domain. J. Biol. Chem. 270: 7795.
11. Bushdid P.B., Brantley D.M., Yull F.E., Blaeuer G.L., Huffman L.H., Niswander L., and Kerr L.D. 1998. Inhibition of NF-κB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis Nature 392: 615.
12. Cao Z., Henzel W.J., and Gao X. 1996a. IRAK: A kinase associated with the interleukin-1 receptor. Science 271: 1128.
13. Cao Z., Xiong J., Takeuchi M., Kurama T., and Goeddel D.V. 1996b. TRAF6 is a signal transducer for interleukin-1. Nature 383: 443.
14. Chinnaiyan A.M., O'Rourke K., Tewari M., and Dixit V.M. 1995. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 81:505.
15. Croston G.E., Cao Z., and Goeddel D.V. 1995. NF-κB activation by interleukin-1 (IL-1) requires an IL-1 receptor-associated protein kinase activity. J. Biol. Chem. 270: 16514.
16. Delhase M., Hayakawa M., Chen Y., and Karin M. 1999. Positive and negative regulation of 1κB kinase activity through IKKß subunit phosphorylation (comments). Science 284: 309.
17. DiDonato J.A., Hayakawa M., Rothwarf D.M., Zandi E., and Karin M. 1997. A cytokine-responsive 1κB kinase that activates the transcription factor NF-κB Nature 388: 548.
18. Franzoso G., Carlson L., Poljak L., Shores E.W., Epstein S., Leonardi A., Grinberg A., Tran T., Scharton-Kersten T., Anver M., Love P., Brown K., and Siebenlist U. 1998. Mice deficient in nuclear factor (NF)-κB/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture. J. Exp. Med. 187: 147.
19. Futterer A., Mink K., Luz A., Kosco-Vilbois M.H., and Pfeffer K. 1998. The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues. Immunity 9: 59-70.
20. Gay N.J. and Keith F.J. 1991. Drosophila Toll and IL-1 receptor (letter). Nature 351: 355.
21. Geisler R., Bergmann A., Hiromi Y., and Nüsslein-Volhard C. 1992. cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the 1κB gene family of vertebrates. Cell 71: 613.
22. Greenfeder S.A., Nunes P., Kwee L., Labow M., Chizzonite R.A., and Ju G. 1995. Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex. J. Biol. Chem. 270: 13757.
23. Grosshans J., Schnorrer F., and Nüsslein-Volhard C. 1999. Oligomerisation of tube and pelle leads to nuclear localisation of dorsal. Mech. Dev. 81: 127.
24. Grosshans J., Bergmann A., Haffter P., and Nusslein-Volhard C. 1994. Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo. Nature 312: 563.
25. Horwitz B.H., Scott M.L., Cherry S.R., Bronson R.T., and Baltimore D. 1997. Failure of lymphopoiesis after adoptive transfer of NF-κB-deficient fetal liver cells. Immunity 6: 765.
26. Hsu H., Xiong J., and Goeddel D.V. 1995. The TNF receptor 1associated protein TRADD signals cell death and NF-κB activation. Cell 81: 495.
27. Hsu H., Shu H.B., Pan M.G., and Goeddel D.V. 1996a. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 84: 299.
28. Hsu H., Huang J., Shu H.B., Baichwal V., and Goeddel D.V. 1996b. TNF-dependent recruitment of the protein kinase RIP to the TNF reccptor-1 signaling complex. Immunity 4: 387.
29. Hu Y., Baud V., Delhase M, Zhang P., Deerinck T., Ellisman M., Johnson R., and Karin M. 1999. Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of 1κB kinase. Science 284: 316.
30. Huang J., Gao X., Li S., and Cao Z. 1997. Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin I receptor accessory protein. Proc. Natl. Acad. Sci. 94: 12829.
31. Ip Y.T., Reach M., Engstrom Y., Kadalayil L., Cai H., Gonzalez-Crespo S., Tatei K., and Levine M. 1993. Dif, a dorsal-related gene that mediates an immune response in Drosophila. Cell 75: 753.
32. Jiang Y., Woronicz J.D., Liu W., and Goeddel D.V. 1999. Prevention of constitutive TNF receptor 1 signaling by silencer of death domains (erratum appears in Science [1999] 283: 1852). Science 283: 543.
33. Kanakaraj P., Schafer P.H., Cavender D.E., Wu Y., Ngo K., Grealish P.F., Wadsworth S.A., Peterson P.A., Siekierka J.J., Harris C.A., and Fung-Leung W.P. 1998. Interleukin (IL)-l receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production. J. Exp. Med. 187: 2073.
34. Kanegae Y., Tavares A.T., Izpisua-Belmonte J.C., and Verma I.M. 1998. Role of Rel/NF-κB transcription factors during the outgrowth of the vertebrate limb. Nature 392: 611.
35. Kelliher M.A., Grimm S., Ishida Y., Kuo F., Stanger B.Z., and Leder P. 1998. The death domain kinase RIP mediates the TNF-induced NF-κB signal. Immunity 8: 297.
36. Kidd S. 1992. Characterization of the Drosophila cactus locus and analysis of interactions between cactus and dorsal proteins. Cell 71: 623.
37. Krasnow S.W., Zhang L.Q., Leung K.Y., Osborn L., Kunkel S., and Nabel G.J. 1991. Tumor necrosis factor-α, interleukin 1, and phorbol myristate acetate are independent activators of NF-κB which differentially activate T cells. Cytokine 3: 372.
38. Lee F.S., Hagler J., Chen Z.J., and Maniatis T. 1997. Activation of the IκB alpha kinase complex by MEKK1, a kinase of the JNK pathway. Cell 88: 213.
39. Lemaitre B., Nicolas E., Michaut L., Reichhart J.M., and Hoffmann J.A. 1996. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86: 973.