Effects of haloperidol and risperidone on neurotensin levels in brain regions and Neurotensin efflux in the ventral striatum of the rat

Neuropsychopharmacology

Volumn 26, Issue 5, 2002, Pages 595-604

  Gruber, Susanne H M ^a,b   Nomikos, George G ^c   Mathé, Aleksander A ^a,b  

^a ST GÖRAN S HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c ELI LILLY AND COMPANY   (United States)

Author keywords

D Amphetamine; Haloperidol; Microdialysis; Neurotensin; Rat brain; Risperidone

Indexed keywords

DEXAMPHETAMINE; HALOPERIDOL; NEUROTENSIN; RISPERIDONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; CORPUS STRIATUM; DRUG EFFECT; FRONTAL CORTEX; HIPPOCAMPUS; MALE; NONHUMAN; OCCIPITAL CORTEX; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; SCHIZOPHRENIA; TISSUE DISTRIBUTION;

ANIMALS; ANTIPSYCHOTIC AGENTS; BASAL GANGLIA; BRAIN; CENTRAL NERVOUS SYSTEM STIMULANTS; DEXTROAMPHETAMINE; DIALYSIS SOLUTIONS; HALOPERIDOL; MALE; MICRODIALYSIS; NEUROTENSIN; RATS; RATS, WISTAR; RISPERIDONE; TISSUE DISTRIBUTION;

EID: 0036199778     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(01)00397-9     Document Type: Article

References (68)

1. Chronic antipsychotic treatment selectively alters nerve growth factor and neuropeptide Y immunoreactivity and the distribution of choline acetyl transferase in rat brain regions
2. Brain-derived neurotrophic factor and tyrosine kinase receptor TrkB in rat brain are significantly altered after haloperidol and risperidone administration
3. Plasma concentrations of risperidone and its 9-hydroxy metabolite and their relationship to dose in schizophrenic patients: Simultaneous determination by a high performance liquid chromatography with electrochemical detection
4. Differential effects of acute dopaminergic D1 and D2 receptor antagonists on proneurotensin mRNA expression in rat striatum
5. Repeated administration of the neurotensin receptor antagonist SR 48692 differentially regulates mesocortical and mesolimbic dopaminergic systems
6. Chronic cocaine increases neurotensin gene expression in the shell of the nucleus accumbens and in discrete regions of the striatum
7. Effects of neurotensin on dopamine release and metabolism in the rat striatum and nucleus accumbens: Cross-validation using in vivo voltammetry and microdialysis
8. The neuropathology of schizophrenic diseases: Historical aspects and present knowledge
9. CSF concentrations of neurotensin in schizophrenia: An investigation of clinical and biochemical correlates
10. 3H] neurotensin binding by unilateral intrastriatal 6-hydroxydopamine injections: Evidence from a receptor autoradiografic study
11. The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami
12. Upregulation of neurotensin mRNA in the rat striatum after acute methamphetamine treatment
13. Neurotensin increases extracellular striatal dopamine levels in vivo
14. Limbic/mesolimbic connections and the pathogenesis of schizophrenia
15. The role of working memory in visual selective attention
16. Numbers of neurotensin-immunoreactive neurons selectively increased in rat ventral striatum following acute haloperidol administration
17. Neurotensin blocks certain amphetamine-induced behaviours
18. Neurotensin concentrations in rat striatum and nucleus accumbens: Futher studies of their regulation
19. Evidence for a substrate of neuronal plasticity based on pre- and postsynaptic neurotensin-dopamine receptor interactions in the neostriatum
20. Regional studies of catecholamines in the rat brain: The disposition of (3H) norepinerphine, (3H) dopamine and (3H) dopa in various regions of the brain
21. The effects of chronic neuroleptic treatment on neurotensin-like immunoreactivity in the rat central nervous system
22. Regulation of information flow in the nucleus accumbens: A model for the pathophysiology of schizophrenia
23. The neuropsychology of schizophrenia
24. Antipsychotics haloperidol and risperidone and psychotomimetic amphetamine affect neuropeptides and monoamines in brain
25. Effects of amphetamine on brain peptides in haloperidol or risperidone pretreted rats
26. Effect of chronic and acute olanzapine on neurotensin levels in rat brain tissue regions and release in ventral striatum
27. Differential effects of antipsychotic and psychotomimetic drugs on neurotensin systems of discrete extrapyramidal and limbic regions
28. Response by the neurotensin systems of the basal ganglia to cocaine treatment
29. Effects of D-amphetamine and phencylidine on behavior and extracellular concentrations of neurotensin and dopamine in the ventral striatum and the medial prefrontal cortex of the rat
30. Differential effect of haloperidol on release of neurotensin in extrapyramidal and limbic systems
31. Occurrence of neurotensin-like immunoreactivity in subpopulations of hypothalamic, mesencephalic and medullary catecholamine neurons
32. Atypical neuroleptic-like behavioral effects of neurotensin
33. Neurotransmitter regulation of dopamine neurons in the ventral tegmental area
34. The neurobiology of neurotensin: Focus on neurotensin-dopamine interactions
35. Differential effects of antipsychotic drugs on the neurotensin content of discrete rat brain nuclei
36. Effects of acute and subchronic administration of typical and atypical drugs on the neurotensin system of the rat brain
37. Acute administration of neuroleptics decreases neurotensin metabolism on intact, regional rat barin slices
38. Anatomy and mechanisms of neurotensin-dopamine interactions in the central nervous system
39. Effect of methamphetamine on neurotensin concentrations in rat brain regions
40. Alterations in regional brain neurotensin concentrations produced by atypical antipsychotic drugs
41. BMY 14802, a potential antipsychotic drug, increases expression of proneurotensin mRNA in the rat striatum
42. A common action of clozapine, haloperidol, and remoxipride on D1- and D2-dopaminergic receptors in the primate cerebral cortex
43. Reduced CFS neurotensin concentration in drug free schizophrenic patients
44. Antipsychotic medication
45. Neuropeptides in brain: Effects of microwave irradiation and decapitation
46. Clozapine and haloperidol block the induction of behavioral sensitization to amphetamine and associated genomic responses in rats
47. Dopamine D2 receptors exert tonic regulation over discrete neurotensin systems of the rat brain
48. Differential effects of haloperidol and clozapine on neurotensin gene transcription in rat neostriatum
49. Differential induction of neurotensin and c-fos gene expression by typical versus atypical antipsychotics
50. Effects of chronic haloperidol and clozapine treatment on neurotensin and c-fos mRNA in rat neostriatal subregions
51. Induction of neurotensin and c-fos mRNA in distinct subregions of rat neostriatum after acute methamphetamine: Comparison with acute haloperidol effects
52. Coexpression of neurotensin and c-fos mRNAs in rat neostriatum neurons following acute haloperidol
53. Risperidone does not elevate neurotensin mRNA in rat nucleus accumbens and caudate-putamen
54. Neurotensin: Antipsychotic drugs, and schizophrenia
55. Interactions between neurotensin and dopamine in the brain: An overview
56. Atypical antipsychotic drugs selectively increase neurotensin efflux in dopamine terminal regions
57. Neurotensin injected into the nucleus accumbens blocks the psychostimulant effects of cocaine but does not attenuate cocaine self-administration in the rat
58. CSF neurotensin concentrations and antipsychotic treatment in schizophrenia and schizoaffective disorders
59. Risperidone compared with new and reference antipsychotic drugs: In vitro and in vivo receptor binding
60. Neurochemical and behavioural effects of neurotensin vs [D-Tyr11] neurotensin on mesolimbic dopaminergic function
61. Blood to brain distrubution of neuroleptics
62. A neural correlate of working memory in the monkey primary visual cortex
63. Microwave irradiation increases recovery of neuropeptides from brain tissues
64. 2-receptors regulate neurotensin release from nucleus accumbens and striatum as measured by in vivo microdialysis
65. Microdialysis assessment of methamphetamine-induced changes in extracellular neurotensin in the striatum and nucleus accumbens
66. Cortical maldevelopment, anti-psychotic drugs, and schizophrenia: A search for common ground
67. Subnormal CSF levels of neurotensin in a subgroup of schizophrenic patients: Normalization after neuroleptic treatment