Hepatic lysosomal enzymes activity and liver morphology after short-time omeprazole administration

Experimental and Toxicologic Pathology

Volumn 53, Issue 6, 2002, Pages 453-459

  Burdan, Franciszek ^a   Siezieniewska, Zofia ^a   Maciejewski, Ryszard ^a   Madej, Barbara ^a   Radzikowska, Elzbieta ^a   Wojtowicz, Zbigniew ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

Acid phosphatase; Beta galactosidase; Cathepsin B; Cathepsin D; Cathepsin L; Lipase; Liver; Lysosomal enzymes; N acetyl glucosaminidase; Omeprazole toxicity; Peritonitis; Sulphatase

Indexed keywords

8 AZAGUANINE; BETA GALACTOSIDASE; CATHEPSIN B; CATHEPSIN D; CATHEPSIN L; EOSIN; HEMATOXYLIN; LYSOSOME ENZYME; N ACETYL BETA GLUCOSAMINIDASE; OMEPRAZOLE; PHOSPHATASE; SODIUM CHLORIDE; SULFATASE; TRIACYLGLYCEROL LIPASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HISTOLOGY; LIVER FUNCTION; LIVER HOMOGENATE; LIVER LYSOSOME; MALE; MICROSCOPY; NONHUMAN; PERIODIC ACID SCHIFF STAIN; PERITONITIS; RAT; SHORT COURSE THERAPY; SPECTROPHOTOMETRY;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0036199154     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1078/0940-2993-00216     Document Type: Article

References (33)

1. Omeprazole is more effective than cimetidine for the relief of all grades of gastro-oesophageal reflux disease-associated heartburn, irrespective of the presence or absence of endoscopic oesophagitis
2. Feedback control of pancreatic secretion in rats. Role of gastric acid secretion
3. Level of malondialdehyde in rat plasma after H2 histaminic receptor blockade
4. Activity of cathepsins and morphological changes in the rat’s liver after ranitidine and famotidine administration
5. The level of malondialdehyde after short-time omeprazole administration
6. Temporary elevation of pancreatic lysosomal enzymes, as a result of the omeprazole-induced peripancreatic inflammation in male Wistar rats
7. Acute disseminated epidermal necrosis due to omeprazole
8. +-ATPase inhibitor a controlled, double-blind study
9. +-ATPase by omeprazole
10. Effect of rabeprazole, a gastric proton pump inhibitor, on biliary and hepatic lysosomal enzymes in rats
11. A review of epidemiologic research on drug-induced acute liver injury using the general practice data base in the United Kingdom
12. Principles in laboratory animals research for experimental purpose
13. Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals
14. Lack of effect of omeprazole, a potent inhibitor of gastric (H+ + K+) ATPase, on hepatic lysosomal integrity and enzyme activity
15. The continuing development of proton pump inhibitors with particular reference to pantoprazole
16. Safety experience from long-term treatment with omeprazole
17. Similarities and differences in the properties of substituted benzimidazoles: A comparison between pantoprazole and related compounds
18. Heartburn without oesophagitis: Efficacy of omeprazole therapy and features determining therapeutic response
19. Protein measurement with folin phenol reagent
20. Drug inducted hepatic injury
21. Thrombocytopenia after treatment with omeprazole
22. +-ATPase
23. The site of acid secretion in the mammalian parietal cell
24. Comparative tolerability profile of omeprazole in clinical trials
25. Liver hyperthermia and oxidative stress: Role of iron and aldehyde production
26. Omeprazole fails to suppress up-regulation of gastric mucosal endothelin-converting enzyme-1 by Helicobacter pylori lipopolysaccharide
27. Review article: Comparison of the pharmacokinetics, acid suppression and efficacy of proton pump inhibitors
28. Omeprazole attenuates oxygen-derived free radical production from human neutrophils
29. US experience with omeprazole in duodenal ulcer. Multicenter double-blind comparative study with ranitidine
30. Effects of omeprazole on neutrophil chemotaxis super oxide production, degranulation, and translation of cytochrome b-245
31. A new mechanism for anti-inflammatory actions of proton pump inhibitors - Inhibitory effects on neutrophil-endothelial cell interactions