Expression of invariant chain (CD 74) and major histocompatibility complex (MHC) class II antigens in the human fetus

Journal of Histochemistry and Cytochemistry

Volumn 50, Issue 4, 2002, Pages 473-482

  Badve, Sunil ^a   Deshpande, Charuhas ^a   Hua, Zhongxue ^a   Lögdberg, Lennart ^a  

^a NORTHWESTERN MEMORIAL HOSPITAL   (United States)

Author keywords

CD74; Discordance; Fetal tissues; Invariant chain; LN2; LN3; MHC class II

Indexed keywords

CD74 ANTIGEN; FETAL ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; FETUS; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; KIDNEY TUBULE; LEYDIG CELL; LUNG ALVEOLUS EPITHELIUM; PRIORITY JOURNAL; RETICULOENDOTHELIAL SYSTEM; SKIN; SMALL INTESTINE MUCOSA; T LYMPHOCYTE;

EID: 0036196962     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215540205000404     Document Type: Article

References (47)

1. Immunohistochemical localization of HLA-DR in human islets of Langerhans
2. An antigen reacting with das-1 monoclonal antibody is ontogenically regulated in diverse organs including liver and indicates sharing of developmental mechanisms among cell lineages
3. Role of intracellular proteases in the processing and transport of class II FILA antigens
4. Sequences homologous to class II MHC W, X, and Y elements mediate constitutive and IFN-gamma-induced expression of human class II-associated invariant chain gene
5. Invariant chain protects class II histocompatibility antigens from binding intact polypeptides in the endoplasmic reticulum
6. The function of invariant chain in class II-restricted antigen presentation
7. Class II transactivator regulates the expression of multiple genes involved in antigen presentation
8. Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts
9. Assembly, transport, and function of MHC class II molecules
10. HLA-expression in pulmonary carcinomas as indication of differentiation and of special subtypes
11. Differential expression of HLA-DR, HLA-DP, HLA-DQ and associated invariant chain (Ii) in normal colorectal mucosa,adenoma and carcinoma
12. The structure of an intermediate in class II MHC maturation: CLIP bound HLA-DR3
13. Expression of HLA-D sub-region products on human colorectal carcinoma
14. Distribution of human leukocyte antigen-ABC and -D/DR antigens in the unfixed human testis
15. Intragonadal regulation of immune system functions
16. Surface expression of the invariant chain (CD74) is independent of concomitant expression of major histocompatibility complex class II antigens
17. Immunoreactivity for LN2 and LN3 distinguishes small cell carcinomas from non-small cell carcinomas in the lung
18. Lymphoid monoclonal antibodies reactive with lung tumors. Diagnostic applications
19. HLA-DM and the MHC class II antigen presentation pathway
20. Peptide exchange in MHC molecules
21. Invariant chain expression in colon neoplasms
22. Up-regulation of the expression of secretory component and HLA molecules in a human colonic cell line by tumor necrosis factor and gamma interferon
23. Transcriptional regulation of HLA class II and invariant chain genes
24. Tissue distribution of the lipocalin alpha-1 m1 microglobulin in the developing human fetus
25. HLA-Dr expression in human fetal intestinal epithelium
26. CD74 workshop panel report
27. Influence of major histocompatibility complex class I and II antigens on survival in colorectal carcinoma
28. Differential expression of Ia and Ia-associated invariant chain in mouse tissues after in vivo treatment with 1FN-gamma
29. Nonimmune human cells can express MHC class II antigens in the absence of invariant chain-an immunohistological study on normal and chronically inflamed small intestine
30. Non-co-ordinate expression of HLA-DR antigens and invariant chain
31. Major his tocompability complex (MHC) class 11 antigen (HLA-DR, DQ, and DP) expression in human fetal endocrine organs and gut
32. Class II antigen-associated invariant chain mRNA in mouse small intestine
33. MHC Class II antigens on lung epithelia of human fetuses and neonates. Ontogeny and expression in lungs with histologic evidence of infection
34. A human Ia cytoplasmic determinant located on multiple forms of invariant chain (gamma, gamma 2, gamma 3)
35. Cathepsins and compartmentalization in antigen presentation
36. Essential role for carhepsin S in MHC class II-associated invariant chain processing and peptide loading
37. Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding
38. Development of intestinal mucosal immunity in fetal life and first postnatal months
39. Discordant expression of major histocompatibility complex class II antigens and invariant chain in interstitial dendritic cells. Implications for self-tolerance and immunity
40. Ontogeny of la messenger RNA in the mouse small intestinal epithelium is modulated by age of weaning and diet
41. Ontogeny of class II MHC mRNA in the mouse small intestinal epithelium
42. Luteinizing hormone triggers a molecular association between its receptor and the major histocompatibility complex class I antigen to produce cell activation
43. Differential Ia antigen expression by autologous human erythroid and lymphoblastoid cell lines
44. Invariant chain distinguishes between exogenous and endogenous antigen presentation pathways
45. Unexpected lack of reactivity of allogeneic anti-Ia monoclonal antibodies with MHC class II molecules expressed by mouse intestinal epithelial cells
46. Evidence of HLA-DR antigen biosynthesis by human keratinocytes in disease
47. An immunohistochemical study of testicular biopsies in childhood acute lymphoblastic leukemia: Reactivity of normal testicular components and leukemic infiltrates