Retrograde transport of ricin

International Journal of Medical Microbiology

Volumn 291, Issue 6-7, 2001, Pages 517-522

  Wesche, Jørgen ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Calreticulin; Endoplasmic reticulum; Golgi apparatus; Proteasomes; Ricin; Sec61p

Indexed keywords

EID: 0036196922     PISSN: 14384221     EISSN: None     Source Type: Journal    
DOI: 10.1078/1438-4221-00161     Document Type: Review

References (31)

1. Ribosome-mediated folding of partially unfolded ricin A chain
2. Introduction of a disulfide bond into ricin A chain decreases the cytotoxicity of the ricin holotoxin
3. A guide to the use of pore-forming toxins for controlled permeabilization of cell membranes
4. An interaction between ricin and calreticulin that may have implications for toxin trafficking
5. RNA N-glycosidase activity of ricin A chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes
6. Inhibition of membrane translocation of diphtheria toxin A fragment by internal disulfide bridges
7. Accumulating evidence suggests that several AB-toxins subvert the endoplasmic reticulum-associated protein degradation pathway to enter target cells
8. The KDEL retrieval system is exploited by Pseudomonas exotoxin A, but not by Shiga-like toxin- 1, during retrograde transport from the Golgi complex to the endoplasmic reticulum
9. Tagging secretory and membrane proteins with a tyrosine sulfation site. Tyrosine sulfation precedes galactosylation and sialylation in COS- 7 cells
10. Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus
11. Toxin entry: Retrograde transport through the secretory pathway
12. Transport of an external Lys-Asp-Glu-Leu (KDEL) protein from the plasma membrane to the endoplasmic reticulum: Studies with cholera toxin in Vero cells
13. Different biological properties of the two constituent peptide chains of ricin, a toxic protein inhibiting protein synthesis
14. Mechanism of action of the toxic lectins abrin and ricin
15. Recycling of proteins between the endoplasmic reticulum and Golgi complex
16. Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol
17. Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium
18. Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles
19. Ricin transport in brefeldin A-treated cells: Correlation between Golgi structure and toxic effect
20. Toxin-induced cell lysis: Protection by 3-methyladenine and cycloheximide
21. Endocytosis, intracellular transport, and cytotoxic action of Shiga toxin and ricin
22. Entry of ricin and Shiga toxin into cells: Molecular mechanisms and medical perspectives
23. Cholera toxin is exported from microsomes by the Sec 61p complex
24. Ricin A chain utilises the endoplasmic reticulum-associated protein degradation pathway to enter the cytosol of yeast
25. Perturbation of vesicular traffic with the carboxylic ionophore monensin
26. Estimation of the amount of internalized ricin that reaches the trans-Golgi network
27. Immunotoxins: Magic bullets or misguided missiles?
28. Addition of an ER retention signal to the ricin A chain increases the cytotoxicity of the holotoxin
29. Characterization of membrane translocation by anthrax protective antigen
30. Dependence of ricin toxicity on translocation of the toxin A chain from the endoplasmic reticulum to the cytosol
31. Disruption of the Golgi apparatus by brefeldin A inhibits the cytotoxicity of ricin, modeccin, and Pseudomonas toxin