Progress towards development of immunoassays for detection of Mycobacterium leprae infection, employing 35kDa antigen: An update

Leprosy Review

Volumn 73, Issue 1, 2002, Pages 9-19

  Parkash, Om ^a  

^a NATIONAL JALMA INSTITUTE FOR LEPROSY AND OTHER MYCOBACTERIAL DISEASES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; MEMBRANE ANTIGEN; MONOCLONAL ANTIBODY; RECOMBINANT ANTIGEN;

ANTIBODY DETECTION; ANTIGEN DETECTION; ANTIGEN SPECIFICITY; B LYMPHOCYTE ACTIVATION; GENETIC ENGINEERING; HUMAN; IMMUNOASSAY; LEPROSY; MONONUCLEAR CELL; MYCOBACTERIUM LEPRAE; REVIEW; T LYMPHOCYTE ACTIVATION;

ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; ANTIGENS, BACTERIAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; LEPROSY; MYCOBACTERIUM LEPRAE; SENSITIVITY AND SPECIFICITY;

EID: 0036196894     PISSN: 03057518     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (43)

1. Classification of leprosy according to immunity. A five-group system
2. Sixth report
3. Sixth report
4. Diagnosis
5. Detection of Mycobacterium leprae infection by PCR
6. Role of polymarase chain reaction in the diagnosis of early leprosy
7. Analysis of the antigenic profile of Mycobacterium leprae: Cross-reactive and unique specificities of human and rabbit antibodies
8. The major native proteins of the leprosy bacillus
9. Identification of an immunostimulating protein from Mycobacterium leprae
10. Characterisation of the gene encoding the immunodominant 35kDa protein of Mycobacterium leprae
11. Molecular and immunological analysis of the Mycobacterium avium homolog of the immunodominant Mycobactrerium leprae 35 kilodalton protein
12. Effective vaccination of mice against leprosy bacillus with subunits of Mycobacterium leprae
13. A 35kDa protein is a major target of the human immune response to Mycobacterium leprae
14. Serodiagnosis of leprosy. The past, the present and some prospects for the future
15. Immunological tools in leprosy controls
16. The contribution of serological tests to leprosy control
17. Definition of species specific and cross-reactive antigenic determinant of Mycobacterium leprae using monoclonal antibodies
18. A serological test for leprosy based on competitive inhibition of monoclonal antibody binding to the MY2a determinant of Mycobacterium leprae
19. Serological survey of leprosy and control subjects by a monoclonal antibody based immunoassay
20. Screening of anti M. leprae antibodies in the blood samples eluted from filter paper blood blots
21. A comparative evaluation of serological assays for lepromatous leprosy
22. Appraisal of two Mycobacterium leprae - Specific serological assays for monitoring chemotherapy in lepromatous (LL/BL) leprosy patients
23. Operational value of serological measurements in multibacillary leprosy patients: Clinical and bacteriological correlates of antibody responses
24. Heterogeneity of serological responses in paucibacillary leprosy: Differential responses to protein and carbohydrate antigen and correlation with clinical parameters
25. A study on the reproducibility of two serological assays for detection of Mycobacterium leprae infection
26. Specific serological detection of leprosy with a recombinant Mycobacterium leprae protein purified from a growing mycobacterial host
27. Rapid method for diagnosis of leprosy by measurement of antibodies to the M. leprae 35kDa protein: Comparison with PGL-1 antibodies detected by ELISA and 'Dip stick' methods
28. Detection of antibodies against phenolic glycolipid-1 (PGL-1), 35kDa and 30-40kDa components of Mycobacterium leprae in the cerebrospinal fluid of leprosy patients
29. Efforts in diagnosing early leprosy using serological techniques
30. Detection of antibodies to 35kDa determinant of M. leprae in urine and serum of leprosy patients
31. Antibodies to phenolic glycolipid 1 and to whole Mycobacterium leprae in leprosy patients: Evolution during therapy
32. Detection of Mycobacterium leprae antigens in sera of leprosy patients by sandwich immunoradiometric assay using monoclonal antibodies
33. Demonstration of mycobacterial antigens in leprosy tissues
34. Identification of Mycobacterium leprae antigens in tissues of leprosy using monoclonal antibodies
35. In situ demonstration of Mycobacterium leprae antigens in leprosy lesions using monoclonal antibodies
36. Demonstration of Mycobacterium leprae specific antigens in leprosy lesions using monoclonal antibodies
37. Antigens of Mycobacterium leprae in the cerebrospinal fluid of leprosy patients: Detection by monoclonal-antibody-based sandwich immunoradiometric assay and avidin/biotin immunoblotting
38. Detection of Mycobacterium leprae antigens in urine of leprosy patients by monoclonal antibody based sandwich immunoradiometric assay and avidin-biotin based immunoblotting
39. T cell response to purified filtrate antigen 85 from Mycobacterium bovis Bacille Calmette-Guerin (BCG) in leprosy patients
40. Immunodiagnostics, including skin tests
41. Specificity and function of immunogenic peptides from the 35 kilodalton protein of Mycobacterium leprae
42. Development of a simple, rapid in vitro cellular assay for bovine tuberculosis based on the production gamma interferon
43. Comparison of a tubercular interferon-gamma assay with the tuberculin skin test in high-risk adults: Effect of human immunodeficiency virus infection