-
1
-
-
18744421286
-
Regional hepatic CYP1A1 and CYP1A2 induction with 2,3,7,8-tetrachlorodibenzo -p-dioxin evaluated with a multi-compartment geometric model of hepatic zonation
-
Andersen ME, Birnbaum LS, Barton HA, Eklund C. (1997). Regional hepatic CYP1A1 and CYP1A2 induction with 2,3,7,8-tetrachlorodibenzo -p-dioxin evaluated with a multi-compartment geometric model of hepatic zonation. ToxicolApplPharmacoll 44: 145-155.
-
(1997)
ToxicolApplPharmacoll
, vol.44
, pp. 145-155
-
-
Andersen, M.E.1
Birnbaum, L.S.2
Barton, H.A.3
Eklund, C.4
-
2
-
-
0008588593
-
Mechanistic modeling of rodent liver tumor promotion at low levels of exposure: An example related to dose-response relationships for 2,3,7,8-tetrachlorodibenzo-p-dioxin
-
Andersen ME, Conolly RB (1998). Mechanistic modeling of rodent liver tumor promotion at low levels of exposure: An example related to dose-response relationships for 2,3,7,8-tetrachlorodibenzo-p-dioxin. BELLE Newsletter 7: 2-8.
-
(1998)
BELLE Newsletter
, vol.7
, pp. 2-8
-
-
Andersen, M.E.1
Conolly, R.B.2
-
3
-
-
0027529301
-
Modeling receptor-mediated processes with dioxin: Implications for pharmacokinetics and risk assessment
-
Andersen ME, Mills JJ, Gargas ML, Kedderis L., Birnbaum LS, Neubert D., Greenlee WF (1993). Modeling receptor-mediated processes with dioxin: Implications for pharmacokinetics and risk assessment. J Risk Anal 13: 25-36.
-
(1993)
J Risk Anal
, vol.13
, pp. 25-36
-
-
Andersen, M.E.1
Mills, J.J.2
Gargas, M.L.3
Kedderis, L.4
Birnbaum, L.S.5
Neubert, D.6
Greenlee, W.F.7
-
4
-
-
0029135146
-
Negative selection in hepatic tumor promotion in relation to cancer risk assessment
-
Andersen ME, Mills JJ, Jirtle RL, Greenlee WF (1995). Negative selection in hepatic tumor promotion in relation to cancer risk assessment. Toxicology 102: 223-237.
-
(1995)
Toxicology
, vol.102
, pp. 223-237
-
-
Andersen, M.E.1
Mills, J.J.2
Jirtle, R.L.3
Greenlee, W.F.4
-
5
-
-
0025733909
-
Dose-dependent acinar induction of cytochrome P450 in rat liver. Evidence for a differential mechanism of induction of P450IA1 by b-naphthoflavone and dioxin
-
Bars RG, Elcombe CR (1991). Dose-dependent acinar induction of cytochrome P450 in rat liver. Evidence for a differential mechanism of induction of P450IA1 by b-naphthoflavone and dioxin. Biochem J 277: 577-580.
-
(1991)
Biochem J
, vol.277
, pp. 577-580
-
-
Bars, R.G.1
Elcombe, C.R.2
-
6
-
-
0024451318
-
Induction of cytochrome P-450 in cultured hepatocytes. The heterogeneous localization of specificisoenzymes using immunocytochemistry
-
Bars RG, Mitchell AM, Wolf CR, Elcombe CR (1989). Induction of cytochrome P-450 in cultured hepatocytes. The heterogeneous localization of specificisoenzymes using immunocytochemistry. Biochem J 262: 151-158.
-
(1989)
Biochem J
, vol.262
, pp. 151-158
-
-
Bars, R.G.1
Mitchell, A.M.2
Wolf, C.R.3
Elcombe, C.R.4
-
7
-
-
0025848853
-
Localization and differential induction of cytochrome P450IVa and acyl-CoA oxidase in rat liver
-
Bell DR, Bars RG, Gibson GG, Elcombe CR (1991). Localization and differential induction of cytochrome P450IVa and acyl-CoA oxidase in rat liver. Biochem J 275: 247-252.
-
(1991)
Biochem J
, vol.275
, pp. 247-252
-
-
Bell, D.R.1
Bars, R.G.2
Gibson, G.G.3
Elcombe, C.R.4
-
8
-
-
0030611602
-
Hepatic foci in rats after diethylnitrosamine initiation and 2,3,7,8-tetrachlorodibenzo-p-dioxin promotion: Evaluation of a quantitative two-cell model and of CYP 1A1/1A2 as a dosimeter
-
Conolly RB, Andersen ME (1997). Hepatic foci in rats after diethylnitrosamine initiation and 2,3,7,8-tetrachlorodibenzo-p-dioxin promotion: Evaluation of a quantitative two-cell model and of CYP 1A1/1A2 as a dosimeter. Toxicol Appl Pharmacol 146: 281-293.
-
(1997)
Toxicol Appl Pharmacol
, vol.146
, pp. 281-293
-
-
Conolly, R.B.1
Andersen, M.E.2
-
9
-
-
0028267158
-
Computer simulation of cell growth governed by stochastic processes: Application to clonal growth cancer models
-
Conolly RB, Kimbell JS (1994). Computer simulation of cell growth governed by stochastic processes: Application to clonal growth cancer models. Toxicol Appl Pharmacol 124: 284-295.
-
(1994)
Toxicol Appl Pharmacol
, vol.124
, pp. 284-295
-
-
Conolly, R.B.1
Kimbell, J.S.2
-
10
-
-
0025597138
-
Genetics of circadian rhythms
-
Hall JC (1990). Genetics of circadian rhythms. Annu Rev Genet 24: 659-687.
-
(1990)
Annu Rev Genet
, vol.24
, pp. 659-687
-
-
Hall, J.C.1
-
11
-
-
0027978109
-
Regulation of mannose-6-phosphate/insulin-like growth factor-II receptors and transforming growth factor beta during liver tumor promotion with phenobarbital
-
Jirtle RL, Hankins GR, Reisenbichier H., Boyer IJ (1994). Regulation of mannose-6-phosphate/insulin-like growth factor-II receptors and transforming growth factor beta during liver tumor promotion with phenobarbital. Carcinogenesis 15: 1473-1478.
-
(1994)
Carcinogenesis
, vol.15
, pp. 1473-1478
-
-
Jirtle, R.L.1
Hankins, G.R.2
Reisenbichier, H.3
Boyer, I.J.4
-
13
-
-
0018074887
-
Results of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo -p-dioxin in rats
-
Kociba RJ, Keyes DG, Beyer JE, Carreon RM, Wade CE, Dittenber DA, Kalnins RP, Frauson LE, Park CN, Banard SD, Hummel RA, Humiston CG (1978). Results of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo -p-dioxin in rats. Toxicol Appl Pharmacol 46: 279-303.
-
(1978)
Toxicol Appl Pharmacol
, vol.46
, pp. 279-303
-
-
Kociba, R.J.1
Keyes, D.G.2
Beyer, J.E.3
Carreon, R.M.4
Wade, C.E.5
Dittenber, D.A.6
Kalnins, R.P.7
Frauson, L.E.8
Park, C.N.9
Banard, S.D.10
Hummel, R.A.11
Humiston, C.G.12
-
14
-
-
0027214951
-
A mechanistic model of the effects of dioxin on gene expression in the rat liver
-
Kohn MC, Lucier GW, Clark GC, Sewall C., Tritscher A., Portier CJ (1993). A mechanistic model of the effects of dioxin on gene expression in the rat liver. Toxicol Appl Pharmacol 120: 138-154.
-
(1993)
Toxicol Appl Pharmacol
, vol.120
, pp. 138-154
-
-
Kohn, M.C.1
Lucier, G.W.2
Clark, G.C.3
Sewall, C.4
Tritscher, A.5
Portier, C.J.6
-
15
-
-
0024328439
-
Hepatic enzymic zonation: A reevaluation of the concept of the liver acinus
-
Lamers WH, Hilberts A., Furt E., Smith J., Jonges GN, Noorden CJFv, Gaasbeck-Janzen JW, Charles B., Moorman AFM (1989). Hepatic enzymic zonation: A reevaluation of the concept of the liver acinus. Hepatology 10: 72-76.
-
(1989)
Hepatology
, vol.10
, pp. 72-76
-
-
Lamers, W.H.1
Hilberts, A.2
Furt, E.3
Smith, J.4
Jonges, G.N.5
Noorden, C.J.F.V.6
Gaasbeck-Janzen, J.W.7
Charles, B.8
Moorman, A.F.M.9
-
16
-
-
0025212601
-
Aphysiological pharmacokinetic description of the tissue distribution and enzyme inducing properties of 2,3,7,8-tetrachlorodibenzo -p-dioxin in the rat
-
Leung HW, Paustenbach DJ, Murray FJ, Andersen ME (1990). Aphysiological pharmacokinetic description of the tissue distribution and enzyme inducing properties of 2,3,7,8-tetrachlorodibenzo -p-dioxin in the rat. Toxicol Appl Pharmacol 103: 399-410.
-
(1990)
Toxicol Appl Pharmacol
, vol.103
, pp. 399-410
-
-
Leung, H.W.1
Paustenbach, D.J.2
Murray, F.J.3
Andersen, M.E.4
-
17
-
-
0027744290
-
Dose response for TCDD promotion of hepatocarcinogenesi s in rats initiated with DEN: Histologic, biochemical, and cell proliferation endpoints
-
Maronpot RR, Foley JF, Takahashi K., Goldsworthy T., Clark G., Tritscher A., Portier C., Lucier G. (1993). Dose response for TCDD promotion of hepatocarcinogenesi s in rats initiated with DEN: Histologic, biochemical, and cell proliferation endpoints. Environ Health Perspect 101: 634-642.
-
(1993)
Environ Health Perspect
, vol.101
, pp. 634-642
-
-
Maronpot, R.R.1
Foley, J.F.2
Takahashi, K.3
Goldsworthy, T.4
Clark, G.5
Tritscher, A.6
Portier, C.7
Lucier, G.8
-
18
-
-
0029070412
-
Alternative models for low dose-response analysis of biochemical and immunological endpoints for tetrachlorodibenzo-p-dioxin
-
McGrath LF, Cooper KR, Georgopoulos P., Gallo MA (1995). Alternative models for low dose-response analysis of biochemical and immunological endpoints for tetrachlorodibenzo-p-dioxin. Regul Toxicol Pharmacol 21: 382-396.
-
(1995)
Regul Toxicol Pharmacol
, vol.21
, pp. 382-396
-
-
McGrath, L.F.1
Cooper, K.R.2
Georgopoulos, P.3
Gallo, M.A.4
-
19
-
-
0028999861
-
Transforming growth factor b1 preferentially induces apoptotic cell death in rat hepatocytes cultured under pericentral-equivalent conditions
-
Ohno K., Ammann P, Fasciati R., Maier P (1995). Transforming growth factor b1 preferentially induces apoptotic cell death in rat hepatocytes cultured under pericentral-equivalent conditions. Toxicol Appl Pharmacol 132: 227-236.
-
(1995)
Toxicol Appl Pharmacol
, vol.132
, pp. 227-236
-
-
Ohno, K.1
Ammann, P.2
Fasciati, R.3
Maier, P.4
-
20
-
-
0026569524
-
Chemical cross-linking of the cytosolic and nuclear forms of the Ah receptor in hepatoma cell lines lele7
-
Perdew GH (1992). Chemical cross-linking of the cytosolic and nuclear forms of the Ah receptor in hepatoma cell lines lele7. Biochem Biophys Res Comm 182: 55-62.
-
(1992)
Biochem Biophys Res Comm
, vol.182
, pp. 55-62
-
-
Perdew, G.H.1
-
21
-
-
0023430918
-
A method to quantitate the relative initiating and promoting potencies of hepatocarcinogeni c agents in their dose-response relationships to altered hepatic foci
-
Pitot HC, Goldsworthy TL, Moran S., Kennan W., Glauert HP, Maronpot RR, Campbell HA (1987). A method to quantitate the relative initiating and promoting potencies of hepatocarcinogeni c agents in their dose-response relationships to altered hepatic foci. Carcinogenesis 8: 1491-1499.
-
(1987)
Carcinogenesis
, vol.8
, pp. 1491-1499
-
-
Pitot, H.C.1
Goldsworthy, T.L.2
Moran, S.3
Kennan, W.4
Glauert, H.P.5
Maronpot, R.R.6
Campbell, H.A.7
-
22
-
-
85045503749
-
2,3,7,8-Tetrachlorodibenzo -p-dioxin and related halogenated aromatic hydrocarbons: Examination of the mechanism of toxicity
-
Poland A., Knudson JC (1982). 2,3,7,8-Tetrachlorodibenzo -p-dioxin and related halogenated aromatic hydrocarbons: Examination of the mechanism of toxicity. Annu Rev Pharmacol Toxicol 32: 531-554.
-
(1982)
Annu Rev Pharmacol Toxicol
, vol.32
, pp. 531-554
-
-
Poland, A.1
Knudson, J.C.2
-
23
-
-
77957183620
-
Ligand/receptor binding for 2,3,7,8-TCDD: Implications for risk assessment
-
Portier C., Tritscher A., Kohn M., Sewall C., Clark G., Edler L., Hoel D., Lucier G. (1993). Ligand/receptor binding for 2,3,7,8-TCDD: Implications for risk assessment. Fundam Appl Toxicol 20: 48-56.
-
(1993)
Fundam Appl Toxicol
, vol.20
, pp. 48-56
-
-
Portier, C.1
Tritscher, A.2
Kohn, M.3
Sewall, C.4
Clark, G.5
Edler, L.6
Hoel, D.7
Lucier, G.8
-
24
-
-
0026625037
-
Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor
-
Reyes H., Reisz-Porszasz S., Hankinson O. (1992). Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor. Science 256: 1193-1195.
-
(1992)
Science
, vol.256
, pp. 1193-1195
-
-
Reyes, H.1
Reisz-Porszasz, S.2
Hankinson, O.3
-
26
-
-
0026730614
-
Classification of members of the AH gene battery
-
Sutter TR, Greenlee WF (1992). Classification of members of the AH gene battery. Chemosphere 25: 222-226.
-
(1992)
Chemosphere
, vol.25
, pp. 222-226
-
-
Sutter, T.R.1
Greenlee, W.F.2
-
27
-
-
0026638156
-
Dose-response relationships for chronic exposure to 2,3,7, 8-tetrachlorodibenzo-p-dioxin in a rat tumor promotion model: Quantification and immunolocalization of CYP1A1 and CYP1A2 in the liver
-
Tritscher AM, Goldstein JA, Portier CJ, McCoy Z., Clark GC, Lucier GW (1992). Dose-response relationships for chronic exposure to 2,3,7, 8-tetrachlorodibenzo-p-dioxin in a rat tumor promotion model: Quantification and immunolocalization of CYP1A1 and CYP1A2 in the liver. Cancer Res 52: 3436-3442.
-
(1992)
Cancer Res
, vol.52
, pp. 3436-3442
-
-
Tritscher, A.M.1
Goldstein, J.A.2
Portier, C.J.3
McCoy, Z.4
Clark, G.C.5
Lucier, G.W.6
-
28
-
-
0033199499
-
P450 gene induction by structurally diverse xenochemicals: Central role of nuclear receptors CAR, PXR, andPPAR
-
Waxman DJ (1999). P450 gene induction by structurally diverse xenochemicals: Central role of nuclear receptors CAR, PXR, andPPAR. Arch Biochem Biophys 369: 11-23.
-
(1999)
Arch Biochem Biophys
, vol.369
, pp. 11-23
-
-
Waxman, D.J.1
-
29
-
-
0025307742
-
Genetic and molecular aspects of 2,3,7,8-tetrchlorodibenzo-p-dioxin activity
-
Whitlock JP (1990). Genetic and molecular aspects of 2,3,7,8-tetrchlorodibenzo-p-dioxin activity. Annu Rev Pharmacol Toxicol 30: 251-277.
-
(1990)
Annu Rev Pharmacol Toxicol
, vol.30
, pp. 251-277
-
-
Whitlock, J.P.1
|