메뉴 건너뛰기




Volumn 30, Issue 1, 2002, Pages 106-111

The Use of Quantitative Histological and Molecular Data for Risk Assessment and Biologically Based Model Development

Author keywords

2,3,7,8 tetrachlorodibenzo p dioxin; cell proliferation; dioxin; immunohistochemistry; phenotypic switching; regional induction; Tumor promotion

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CYTOCHROME P450; PROTEIN; TUMOR PROMOTER;

EID: 0036192161     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230252824789     Document Type: Article
Times cited : (3)

References (29)
  • 1
    • 18744421286 scopus 로고    scopus 로고
    • Regional hepatic CYP1A1 and CYP1A2 induction with 2,3,7,8-tetrachlorodibenzo -p-dioxin evaluated with a multi-compartment geometric model of hepatic zonation
    • Andersen ME, Birnbaum LS, Barton HA, Eklund C. (1997). Regional hepatic CYP1A1 and CYP1A2 induction with 2,3,7,8-tetrachlorodibenzo -p-dioxin evaluated with a multi-compartment geometric model of hepatic zonation. ToxicolApplPharmacoll 44: 145-155.
    • (1997) ToxicolApplPharmacoll , vol.44 , pp. 145-155
    • Andersen, M.E.1    Birnbaum, L.S.2    Barton, H.A.3    Eklund, C.4
  • 2
    • 0008588593 scopus 로고    scopus 로고
    • Mechanistic modeling of rodent liver tumor promotion at low levels of exposure: An example related to dose-response relationships for 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Andersen ME, Conolly RB (1998). Mechanistic modeling of rodent liver tumor promotion at low levels of exposure: An example related to dose-response relationships for 2,3,7,8-tetrachlorodibenzo-p-dioxin. BELLE Newsletter 7: 2-8.
    • (1998) BELLE Newsletter , vol.7 , pp. 2-8
    • Andersen, M.E.1    Conolly, R.B.2
  • 4
    • 0029135146 scopus 로고
    • Negative selection in hepatic tumor promotion in relation to cancer risk assessment
    • Andersen ME, Mills JJ, Jirtle RL, Greenlee WF (1995). Negative selection in hepatic tumor promotion in relation to cancer risk assessment. Toxicology 102: 223-237.
    • (1995) Toxicology , vol.102 , pp. 223-237
    • Andersen, M.E.1    Mills, J.J.2    Jirtle, R.L.3    Greenlee, W.F.4
  • 5
    • 0025733909 scopus 로고
    • Dose-dependent acinar induction of cytochrome P450 in rat liver. Evidence for a differential mechanism of induction of P450IA1 by b-naphthoflavone and dioxin
    • Bars RG, Elcombe CR (1991). Dose-dependent acinar induction of cytochrome P450 in rat liver. Evidence for a differential mechanism of induction of P450IA1 by b-naphthoflavone and dioxin. Biochem J 277: 577-580.
    • (1991) Biochem J , vol.277 , pp. 577-580
    • Bars, R.G.1    Elcombe, C.R.2
  • 6
    • 0024451318 scopus 로고
    • Induction of cytochrome P-450 in cultured hepatocytes. The heterogeneous localization of specificisoenzymes using immunocytochemistry
    • Bars RG, Mitchell AM, Wolf CR, Elcombe CR (1989). Induction of cytochrome P-450 in cultured hepatocytes. The heterogeneous localization of specificisoenzymes using immunocytochemistry. Biochem J 262: 151-158.
    • (1989) Biochem J , vol.262 , pp. 151-158
    • Bars, R.G.1    Mitchell, A.M.2    Wolf, C.R.3    Elcombe, C.R.4
  • 7
    • 0025848853 scopus 로고
    • Localization and differential induction of cytochrome P450IVa and acyl-CoA oxidase in rat liver
    • Bell DR, Bars RG, Gibson GG, Elcombe CR (1991). Localization and differential induction of cytochrome P450IVa and acyl-CoA oxidase in rat liver. Biochem J 275: 247-252.
    • (1991) Biochem J , vol.275 , pp. 247-252
    • Bell, D.R.1    Bars, R.G.2    Gibson, G.G.3    Elcombe, C.R.4
  • 8
    • 0030611602 scopus 로고    scopus 로고
    • Hepatic foci in rats after diethylnitrosamine initiation and 2,3,7,8-tetrachlorodibenzo-p-dioxin promotion: Evaluation of a quantitative two-cell model and of CYP 1A1/1A2 as a dosimeter
    • Conolly RB, Andersen ME (1997). Hepatic foci in rats after diethylnitrosamine initiation and 2,3,7,8-tetrachlorodibenzo-p-dioxin promotion: Evaluation of a quantitative two-cell model and of CYP 1A1/1A2 as a dosimeter. Toxicol Appl Pharmacol 146: 281-293.
    • (1997) Toxicol Appl Pharmacol , vol.146 , pp. 281-293
    • Conolly, R.B.1    Andersen, M.E.2
  • 9
    • 0028267158 scopus 로고
    • Computer simulation of cell growth governed by stochastic processes: Application to clonal growth cancer models
    • Conolly RB, Kimbell JS (1994). Computer simulation of cell growth governed by stochastic processes: Application to clonal growth cancer models. Toxicol Appl Pharmacol 124: 284-295.
    • (1994) Toxicol Appl Pharmacol , vol.124 , pp. 284-295
    • Conolly, R.B.1    Kimbell, J.S.2
  • 10
    • 0025597138 scopus 로고
    • Genetics of circadian rhythms
    • Hall JC (1990). Genetics of circadian rhythms. Annu Rev Genet 24: 659-687.
    • (1990) Annu Rev Genet , vol.24 , pp. 659-687
    • Hall, J.C.1
  • 11
    • 0027978109 scopus 로고
    • Regulation of mannose-6-phosphate/insulin-like growth factor-II receptors and transforming growth factor beta during liver tumor promotion with phenobarbital
    • Jirtle RL, Hankins GR, Reisenbichier H., Boyer IJ (1994). Regulation of mannose-6-phosphate/insulin-like growth factor-II receptors and transforming growth factor beta during liver tumor promotion with phenobarbital. Carcinogenesis 15: 1473-1478.
    • (1994) Carcinogenesis , vol.15 , pp. 1473-1478
    • Jirtle, R.L.1    Hankins, G.R.2    Reisenbichier, H.3    Boyer, I.J.4
  • 16
    • 0025212601 scopus 로고
    • Aphysiological pharmacokinetic description of the tissue distribution and enzyme inducing properties of 2,3,7,8-tetrachlorodibenzo -p-dioxin in the rat
    • Leung HW, Paustenbach DJ, Murray FJ, Andersen ME (1990). Aphysiological pharmacokinetic description of the tissue distribution and enzyme inducing properties of 2,3,7,8-tetrachlorodibenzo -p-dioxin in the rat. Toxicol Appl Pharmacol 103: 399-410.
    • (1990) Toxicol Appl Pharmacol , vol.103 , pp. 399-410
    • Leung, H.W.1    Paustenbach, D.J.2    Murray, F.J.3    Andersen, M.E.4
  • 17
    • 0027744290 scopus 로고
    • Dose response for TCDD promotion of hepatocarcinogenesi s in rats initiated with DEN: Histologic, biochemical, and cell proliferation endpoints
    • Maronpot RR, Foley JF, Takahashi K., Goldsworthy T., Clark G., Tritscher A., Portier C., Lucier G. (1993). Dose response for TCDD promotion of hepatocarcinogenesi s in rats initiated with DEN: Histologic, biochemical, and cell proliferation endpoints. Environ Health Perspect 101: 634-642.
    • (1993) Environ Health Perspect , vol.101 , pp. 634-642
    • Maronpot, R.R.1    Foley, J.F.2    Takahashi, K.3    Goldsworthy, T.4    Clark, G.5    Tritscher, A.6    Portier, C.7    Lucier, G.8
  • 18
    • 0029070412 scopus 로고
    • Alternative models for low dose-response analysis of biochemical and immunological endpoints for tetrachlorodibenzo-p-dioxin
    • McGrath LF, Cooper KR, Georgopoulos P., Gallo MA (1995). Alternative models for low dose-response analysis of biochemical and immunological endpoints for tetrachlorodibenzo-p-dioxin. Regul Toxicol Pharmacol 21: 382-396.
    • (1995) Regul Toxicol Pharmacol , vol.21 , pp. 382-396
    • McGrath, L.F.1    Cooper, K.R.2    Georgopoulos, P.3    Gallo, M.A.4
  • 19
    • 0028999861 scopus 로고
    • Transforming growth factor b1 preferentially induces apoptotic cell death in rat hepatocytes cultured under pericentral-equivalent conditions
    • Ohno K., Ammann P, Fasciati R., Maier P (1995). Transforming growth factor b1 preferentially induces apoptotic cell death in rat hepatocytes cultured under pericentral-equivalent conditions. Toxicol Appl Pharmacol 132: 227-236.
    • (1995) Toxicol Appl Pharmacol , vol.132 , pp. 227-236
    • Ohno, K.1    Ammann, P.2    Fasciati, R.3    Maier, P.4
  • 20
    • 0026569524 scopus 로고
    • Chemical cross-linking of the cytosolic and nuclear forms of the Ah receptor in hepatoma cell lines lele7
    • Perdew GH (1992). Chemical cross-linking of the cytosolic and nuclear forms of the Ah receptor in hepatoma cell lines lele7. Biochem Biophys Res Comm 182: 55-62.
    • (1992) Biochem Biophys Res Comm , vol.182 , pp. 55-62
    • Perdew, G.H.1
  • 21
    • 0023430918 scopus 로고
    • A method to quantitate the relative initiating and promoting potencies of hepatocarcinogeni c agents in their dose-response relationships to altered hepatic foci
    • Pitot HC, Goldsworthy TL, Moran S., Kennan W., Glauert HP, Maronpot RR, Campbell HA (1987). A method to quantitate the relative initiating and promoting potencies of hepatocarcinogeni c agents in their dose-response relationships to altered hepatic foci. Carcinogenesis 8: 1491-1499.
    • (1987) Carcinogenesis , vol.8 , pp. 1491-1499
    • Pitot, H.C.1    Goldsworthy, T.L.2    Moran, S.3    Kennan, W.4    Glauert, H.P.5    Maronpot, R.R.6    Campbell, H.A.7
  • 22
    • 85045503749 scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo -p-dioxin and related halogenated aromatic hydrocarbons: Examination of the mechanism of toxicity
    • Poland A., Knudson JC (1982). 2,3,7,8-Tetrachlorodibenzo -p-dioxin and related halogenated aromatic hydrocarbons: Examination of the mechanism of toxicity. Annu Rev Pharmacol Toxicol 32: 531-554.
    • (1982) Annu Rev Pharmacol Toxicol , vol.32 , pp. 531-554
    • Poland, A.1    Knudson, J.C.2
  • 24
    • 0026625037 scopus 로고
    • Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor
    • Reyes H., Reisz-Porszasz S., Hankinson O. (1992). Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor. Science 256: 1193-1195.
    • (1992) Science , vol.256 , pp. 1193-1195
    • Reyes, H.1    Reisz-Porszasz, S.2    Hankinson, O.3
  • 26
    • 0026730614 scopus 로고
    • Classification of members of the AH gene battery
    • Sutter TR, Greenlee WF (1992). Classification of members of the AH gene battery. Chemosphere 25: 222-226.
    • (1992) Chemosphere , vol.25 , pp. 222-226
    • Sutter, T.R.1    Greenlee, W.F.2
  • 27
    • 0026638156 scopus 로고
    • Dose-response relationships for chronic exposure to 2,3,7, 8-tetrachlorodibenzo-p-dioxin in a rat tumor promotion model: Quantification and immunolocalization of CYP1A1 and CYP1A2 in the liver
    • Tritscher AM, Goldstein JA, Portier CJ, McCoy Z., Clark GC, Lucier GW (1992). Dose-response relationships for chronic exposure to 2,3,7, 8-tetrachlorodibenzo-p-dioxin in a rat tumor promotion model: Quantification and immunolocalization of CYP1A1 and CYP1A2 in the liver. Cancer Res 52: 3436-3442.
    • (1992) Cancer Res , vol.52 , pp. 3436-3442
    • Tritscher, A.M.1    Goldstein, J.A.2    Portier, C.J.3    McCoy, Z.4    Clark, G.C.5    Lucier, G.W.6
  • 28
    • 0033199499 scopus 로고    scopus 로고
    • P450 gene induction by structurally diverse xenochemicals: Central role of nuclear receptors CAR, PXR, andPPAR
    • Waxman DJ (1999). P450 gene induction by structurally diverse xenochemicals: Central role of nuclear receptors CAR, PXR, andPPAR. Arch Biochem Biophys 369: 11-23.
    • (1999) Arch Biochem Biophys , vol.369 , pp. 11-23
    • Waxman, D.J.1
  • 29
    • 0025307742 scopus 로고
    • Genetic and molecular aspects of 2,3,7,8-tetrchlorodibenzo-p-dioxin activity
    • Whitlock JP (1990). Genetic and molecular aspects of 2,3,7,8-tetrchlorodibenzo-p-dioxin activity. Annu Rev Pharmacol Toxicol 30: 251-277.
    • (1990) Annu Rev Pharmacol Toxicol , vol.30 , pp. 251-277
    • Whitlock, J.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.