Kinetic resolution of an indan derivative using Bacillus sp. SUI-12: Synthesis of a key intermediate of the melatonin receptor agonist TAK-375

Journal of Bioscience and Bioengineering

Volumn 93, Issue 1, 2002, Pages 44-47

  Tarui, Naoki ^a   Nagano, Yoichi ^a   Sakane, Takeshi ^a   Matsumoto, Kiyoharu ^a   Kawada, Mitsuru ^a   Uchikawa, Osamu ^a   Ohkawa, Shigenori ^a   Nakahama, Kazuo ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

Bacillus sp. SUI 12; Chiral indan derivative; Kinetic resolution; Melatonin receptor agonist; Scale up

Indexed keywords

CATALYST SELECTIVITY; ENZYMES; HYDROLYSIS; ISOMERS; REACTION KINETICS;

ENANTIOSELECTIVITY;

ORGANIC COMPOUNDS;

2 [2 (1,6,7,8 TETRAHYDRO 2H INDENO[5,4 B]FURAN 8 YL)ETHYLAMINE]; ACETAMIDE DERIVATIVE; AMIDE; AMINE; FURAN DERIVATIVE; INDAN DERIVATIVE; MELATONIN RECEPTOR; RAMELTEON; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS; CATALYSIS; CHEMICAL REACTION; CHIRALITY; CULTURE MEDIUM; DRUG SYNTHESIS; ENANTIOMER; ENANTIOSELECTIVITY; HYDROLYSIS; NONHUMAN; REACTION ANALYSIS;

BACILLUS SP.; POSIBACTERIA;

EID: 0036191891     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1389-1723(02)80052-4     Document Type: Article

References (10)

1. Designing chiral libraries for drug discovery
2. Stoichiometric asymmetric processes
3. Lipases: Interfacial enzymes with attractive applications
4. Enzymatic kinetic resolution of piperidine atropisomers: Synthesis of a key intermediate of the farnesyl protein transferase inhibitor, SCH66336
5. Dynamic kinetic resolution of suprofen thioester via coupled trioctylamine and lipase catalysis
6. Non-conventional hydrolase chemistry: Amide and carbamate bond formation catalyzed by lipases
7. First preparation of enantiopure indane monomer, (S)-(-)- and (R)-(+)-2,3-dihydro3-(4′-hydroxyphenyl)-1,1,3-trimethyl-1H-inden-5-01, via a unique enantio- and regioselective enzymatic kinetic resolution
8. Neuropharmacological properties of TAK-375, a novel melatonin ML receptor agonist