Effects of cyclosporin A by aerosol on airway hyperresponsiveness and inflammation in guinea pigs

Acta Pharmacologica Sinica

Volumn 23, Issue 3, 2002, Pages 243-247

  Xie, Qiang Min ^a   Chen, Ji Qiang ^a   Shen, Wen Hui ^a   Yang, Qiu Huo ^a   Bian, Ru Lian ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Acetylcholine; Asthma; Cyclosporins; Eosinophils; Guinea pigs; Histamine; Ovalbumin

Indexed keywords

ACETYLCHOLINE; ANTIASTHMATIC AGENT; CYCLOSPORIN A; DEXAMETHASONE; HISTAMINE; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; OVALBUMIN;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; DRUG EFFECT; EOSINOPHIL; GUINEA PIG; HISTOPATHOLOGY; IN VIVO STUDY; INFLAMMATORY INFILTRATE; LUNG LAVAGE; LUNG RESISTANCE; LYMPHOCYTE; NEUTROPHIL; NONHUMAN; RESPIRATORY TRACT INFLAMMATION; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG POTENTIATION; FEMALE; MALE; PATHOLOGY;

ACETYLCHOLINE; AEROSOLS; ANIMALS; ANTI-ASTHMATIC AGENTS; ASTHMA; BRONCHOALVEOLAR LAVAGE; CYCLOSPORINE; DEXAMETHASONE; DRUG SYNERGISM; EOSINOPHILS; FEMALE; GUINEA PIGS; HISTAMINE; IMMUNOSUPPRESSIVE AGENTS; MALE; OVALBUMIN;

EID: 0036189185     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

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3. Double-blind placebo-controlled study of cyclosporin A as a corticosteroid-sparing agent in corticosteroid-dependent asthma
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6. The effect of different corticosteroids and cyclosporin A on interleukin-4 and interleukin-5 release from murine TH2-type T cells
7. Cyclosporin A and FK506 reduce interleukin-5 mRNA abundance by inhibiting gene transcription
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13. Pharmacokinetics, pharmacodynamics and safety of inhaled cyclosporin A (ADI628) after single and repeated administration in healthy male and female subjects and asthmatic patients
14. Latest advances in the development of dry powder inhalers