In vivo HIV-1 compartmentalisation: Drug resistance-associated mutation distribution

Journal of Medical Virology

Volumn 66, Issue 1, 2002, Pages 8-12

  Devereux, Helen L ^a   Burke, Andy ^a   Lee, Christine A ^a   Johnson, Margaret A ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Antiretroviral therapy; Compartmentalisation; HIV resistance mutations; Postmortem tissues

Indexed keywords

ANTIRETROVIRUS AGENT; ASPARAGINE; ASPARTIC ACID; DIDANOSINE; INDINAVIR; ISOLEUCINE; LAMIVUDINE; METHIONINE; NELFINAVIR; NEVIRAPINE; PROTEINASE; RNA DIRECTED DNA POLYMERASE; SAQUINAVIR; STAVUDINE; VIRUS DNA; VIRUS RNA; ZALCITABINE; ZIDOVUDINE;

ADULT; ARTICLE; CASE REPORT; CONSENSUS SEQUENCE; ESOPHAGUS; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN TISSUE; IN VIVO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMA; PROVIRUS; SEQUENCE ANALYSIS; VIRAL GENETICS; VIRUS MUTATION; VIRUS RESISTANCE;

ADULT; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; AUTOPSY; DRUG RESISTANCE, VIRAL; GENOTYPE; HIV INFECTIONS; HIV PROTEASE; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; ORGAN SPECIFICITY; SEQUENCE ANALYSIS, DNA; VIRAL LOAD;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0036188864     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmv.2104     Document Type: Article

References (13)

1. Quantitative differences in the distribution of zidovudine resistance mutations in multiple postmortem tissues from AIDS patients
2. A pilot study of the short-term effects of antiretroviral management based on plasma genotypic antiretroviral resistance testing (GART) in patients failing antiretroviral therapy
3. Reverse transcriptase sequence of paired isolates of cerebrospinal fluid and blood from patients infected with human immunodeficiency virus type 1 during zidovudine treatment
4. Drug-resistance genotyping in HIV-1 therapy: The VIRADAPT randomised controlled trial
5. Resistance of HIV-1 to antiretroviral agents in blood and seminal plasma: Implications for transmission
6. Human immunodeficiency virus replication and genotypic resistance in blood and lymph nodes after a year of potent antiretroviral therapy
7. Antiretroviral drug resistance testing in adults with HIV infection. Implications for clinical management
8. A microtitre format point mutation assay: Application to the detection of drug resistance in human immunodeficiency virus type-1 infected patients treated with zidovudine
9. Detection of drug resistance mutations in the human immunodeficiency virus type 1 (HIV-1) pol gene: Differences in semen and blood HIV-1 RNA and proviral DNA
10. Efficacy of adding indinavir to previous reverse transcriptase nucleoside analogues in relation to genotypic and phenotypic resistance development in advanced HIV-1-infected patients
11. Accumulation of defective viral genomes in peripheral blood mononuclear cells of human immunodeficiency virus type 1-infected individuals
12. Antiretroviral resistance mutations in human immunodeficiency virus type i reverse transcriptase and protease from paired cerebrospinal fluid and plasma samples
13. In vivo compartmentalization of human immunodeficiency virus: Evidence from the examination of pol sequences from autopsy tissues