Phosphodiesterase isoenzyme families in human osteoarthritis chondrocytes - Functional importance of phosphodiesterase 4

British Journal of Pharmacology

Volumn 135, Issue 3, 2002, Pages 609-618

  Tenor, Hermann ^a   Hedbom, Erik ^b   Häuselmann, Hans Jörg ^b   Schudt, Christian ^a   Hatzelmann, Armin ^a  

^a ALTANA PHARMA AG   (Germany)

^b KLINIK IM PARK   (Switzerland)

Author keywords

Chondrocytes; Cyclic AMP; Interleukin 1 ; Nitric oxide; Phosphodiesterase

Indexed keywords

ALGINIC ACID; CYCLIC AMP; CYCLIC NUCLEOTIDE; INDOMETACIN; INTERLEUKIN 1BETA; MOTAPIZONE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHODIESTERASE; PHOSPHODIESTERASE IV; PICLAMILAST; PROSTAGLANDIN E2; ROFLUMILAST; SILDENAFIL;

ARTICLE; AUTOCRINE EFFECT; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL CULTURE; CELL PROTECTION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYDROLYSIS; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN FAMILY;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; CELLS, CULTURED; CHONDROCYTES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HUMANS; INTERLEUKIN-1; ISOENZYMES; NITRIC OXIDE; OSTEOARTHRITIS; PHOSPHODIESTERASE INHIBITORS; UP-REGULATION;

EID: 0036177992     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704480     Document Type: Article

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