The nonapoptotic pathway mediating thymidine kinase/ganciclovir toxicity is reduced by signal from adenovirus type 5 early region 4

Molecular Therapy

Volumn 5, Issue 2, 2002, Pages 170-176

  Katabi, Maha ^a   Yuan, Shala ^b   Chan, Helen ^b   Galipeau, Jacques ^b   Batist, Gerald ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Adenoviral vectors; Adenovirus early region 4; Apoptosis; Ganciclovir; Suicide gene therapy; Thymidine kinase

Indexed keywords

ADENOVIRUS VECTOR; DNA; GANCICLOVIR; THYMIDINE KINASE; VIRUS PROTEIN;

ADENOVIRUS 5; APOPTOSIS; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DNA DEGRADATION; DRUG EFFECT; GENETIC CODE; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; NICK END LABELING; NUCLEOSOME; RETROVIRUS; SIGNAL TRANSDUCTION; SUICIDE GENE THERAPY; TREATMENT OUTCOME; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; HUMAN ADENOVIRUS TYPE 5; UNIDENTIFIED RETROVIRUS;

EID: 0036171068     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2002.0521     Document Type: Article

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