Comparative assessment of leflunomide and methotrexate for the treatment of rheumatoid arthritis, by dynamic enhanced magnetic resonance imaging

Arthritis and Rheumatism

Volumn 46, Issue 2, 2002, Pages 366-372

  Reece, Richard J ^a   Kraan, Maarten C ^b   Radjenovic, Aleksandra ^a   Veale, Douglas J ^a   O'Connor, P J ^a   Ridgway, John P ^a   Gibbon, W W ^a   Breedveld, Ferdinand C ^b   Tak, Paul P ^b   Emery, Paul ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM; LEFLUNOMIDE; METHOTREXATE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTRAST ENHANCEMENT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; FEMALE; HUMAN; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RHEUMATOID ARTHRITIS; SYNOVITIS; TREATMENT OUTCOME;

ADULT; AGED; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; ISOXAZOLES; MAGNETIC RESONANCE IMAGING; MALE; METHOTREXATE; MIDDLE AGED; PROSPECTIVE STUDIES; SYNOVITIS; TREATMENT OUTCOME;

EID: 0036169558     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.10084     Document Type: Article

References (26)

1. Measurement and prediction of radiological progression in early rheumatoid arthritis
2. Placebo-controlled studies in rheumatoid arthritis: Ethical issues
3. Placebo-controlled trials and activecontrol trials in the evaluation of new treatments. Part 1: Ethical and scientific issues
4. Magnetic resonance imaging in early inflammatory arthritis: What is its role?
5. Radiographic imaging: The "gold standard" for assessment of disease progression in rheumatoid arthritis
6. The relationship between synovitis and bone changes in early untreated rheumatoid arthritis: A controlled magnetic resonance imaging study
7. MR imaging of the knee in acute rheumatoid arthritis: Synovial uptake of gadolinium-DOTA
8. Quantification of synovitis by MRI: Correlation between dynamic and static gadolinium-enhanced magnetic resonance imaging and microscopic signs of synovial inflammation
9. Magnetic resonance imaging-determined synovial membrane and joint effusion volumes in rheumatoid arthritis and osteoarthritis: Comparison with the macroscopic and microscopic appearance of the synovium
10. Quantitative assessment of synovial inflammation by dynamic gadolinium-enhanced magnetic resonance imaging: A study of the effect of intra-articular methylprednisolone on the rate of early synovial enhancement
11. Dynamic magnetic resonance imaging for the evaluation of synovitis in patients with rheumatoid arthritis
12. Quantitative assessment of the rheumatoid synovial microvascular bed by gadolinium-DTPA enhanced magnetic resonance imaging
13. Sulfasalazine in early rheumatoid arthritis: A 48-week double-blind, prospective, placebo-controlled study
14. Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: A double-blind, randomised, multicentre trial
15. Treatment with leflunomide slows radiographic progression of rheumatoid arthritis: Results from three randomized controlled trials of leflunomide in patients with active rheumatoid arthritis
16. Radiologic evidence of disease modification in rheumatoid arthritis patients treated with cyclosporine: Results of a 48-week multicenter study comparing low-dose cyclosporine with placebo
17. Treatment of active rheumatoid arthritis with leflunomide compared to placebo and methotrexate
18. A comparison of the efficacy and safety of leflunomide and methotrexate for the treatment of rheumatoid arthritis
19. Mechanism of action for leflunomide in rheumatoid arthritis
20. Modulation of inflammation and metalloproteinase expression in synovial tissue by leflunomide and methotrexate in patients with active rheumatoid arthritis: Findings in a prospective, randomized, double-blind, parallel-design clinical trial in thirtynine patients at two centers
21. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
22. Assessment of patient satisfaction in activities of daily living using a modified Stanford Health Assessment Questionnaire
23. American College of Rheumatology preliminary definition of improvement in rheumatoid arthritis
24. Quantification of inflammation in the wrist with gadolinium-enhanced MR imaging and PET with 2-[F-18]-fluoro-2-deoxy-D-glucose
25. Leflunomide: Efficacy and safety in clinical trials for the treatment of rheumatoid arthritis
26. A 1-year follow up study of dynamic magnetic resonance imaging in early rheumatoid arthritis reveals synovitis to be increased in shared epitope-positive patients and predictive of erosions at 1 year