Analyzing the repressive function of Ultraspiracle, the Drosophila RXR, in Drosophila eye development

Mechanisms of Development

Volumn 111, Issue 1-2, 2002, Pages 89-98

  Ghbeish, Nora ^a,b   McKeown, Michael ^a,c  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BROWN UNIVERSITY   (United States)

Author keywords

Activation; Broad Complex; Ecdysone; Ecdysone receptor; Eye development; Morphogenetic furrow; Nuclear receptor; Repression; Ultraspiracle

Indexed keywords

ECDYSONE; ISOPROTEIN; PROTEIN; ULTRASPIRACLE PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DROSOPHILA; EYE DEVELOPMENT; MOLECULAR CLONING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; ECDYSONE; EYE; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLYCOPROTEINS; INSECT PROTEINS; LARVA; MALE; MUTATION; RECEPTORS, STEROID; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS; WING;

INSECTA;

EID: 0036169474     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(01)00610-4     Document Type: Article

References (39)

1. Drosophila eye development: Notch and Delta amplify a neurogenic pattern conferred on the morphogenetic furrow by scabrous
2. Spacing differentiation in the developing Drosophila eye: A fibrinogen-related lateral inhibitor encoded by scabrous
3. A switch in broad-complex zinc-finger isoform expression is regulated posttranscriptionally during the metamorphosis of Drosophila imaginal discs
4. Identification and characterization of a neuron-specific nuclear antigen in Drosophila
5. An extensive 3′ cis-regulatory region directs the imaginal disk expression of decapentaplegic, a member of the TGF-beta family in Drosophila
6. Patterns of expression of cut, a protein required for external sensory organ development in wild-type and cut mutant Drosophila embryos
7. Postembryonic patterns of expression of cut, a locus regulating sensory organ identity in Drosophila
8. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
9. Ecdysone pathway is required for furrow progression in the developing Drosophila eye
10. Broad-complex, but not Ecdysone receptor, is required for progression of the morphogenetic furrow in the Drosophila eye
11. Hairy and emc negatively regulate morphogenetic furrow progression in the Drosophila eye
12. Ecdysteroids govern two phases of eye development during metamorphosis of the moth, Manduca sexta
13. DNA binding and heteromerization of the Drosophila transcription factor chorion factor 1/ultraspiracle
14. Hedgehog directly controls initiation and propagation of retinal differentiation in the Drosophila eye
15. Differential expression of Broad-Complex transcription factors may forecast tissue-specific developmental fates during Drosophila metamorphosis
16. The Pax2 homolog sparkling is required for development of cone and pigment cells in the Drosophila eye
17. The dual role of ultraspiracle, the Drosophila retinoid X receptor, in the ecdysone response
18. tramtrack acts downstream of numb to specify distinct daughter cell fates during asymmetric cell divisions in the Drosophila PNS
19. Control of daughter cell fates during asymmetric division: Interaction of Numb and Notch
20. The TBFB homologue dpp and the segment polarity gene hedgehog are required for propagation of a morphogenetic wave in the Drosophila retina
21. Dual bar homeo box genes of Drosophila required in two photoreceptor cells, R1 and R6, and primary pigment cells for normal eye development
22. atonal is the proneural gene for Drosophila photoreceptors
23. Temporal coordination of regulatory gene expression by the steroid hormone ecdysone
24. The Drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily
25. Repression of Drosophila photoreceptor cell fate through cooperative action of two transcriptional repressors Yan and tramtrack
26. The scabrous protein can act as an extracellular antagonist of notch signaling in the Drosophila wing
27. wingless and patched are negative regulators of the morphogenetic furrow and can affect polarity in the developing Drosophila compound eye
28. The segment polarity gene hedgehog is required for progression of the morphogenetic furrow in the developing Drosophila eye
29. Isolation and expression of scabrous, a gene regulating neurogenesis in Drosophila
30. Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor
31. The Drosophila retinoid X receptor homologue ultraspiracle functions in both female reproduction and eye morphogenesis
32. Scabrous complexes with Notch to mediate boundary formation
33. The RXR ortholog USP suppresses early metamorphic processes in Drosophila in the absence of ecdysteroids
34. Regulation of furrow progression in the Drosophila eye by cAMP-dependent protein kinase A
35. SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development
36. Analysis of genetic mosaics in developing and adult Drosophila tissues
37. Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation
38. Functional ecdysone receptor is the product of EcR and Ultraspiracle genes
39. A role for Ultraspiracle, the Drosophila RXR, in morphogenetic furrow movement and photoreceptor cluster formation