Synthesis and antibacterial activity of pyridazino[4,3-b]indole-4-carboxylic acids carrying different substituents at N-2

Farmaco

Volumn 57, Issue 1, 2002, Pages 63-69

  Palluotto, Fausta ^a   Campagna, Francesco ^a   Carotti, Angelo ^a   Ferappi, Marcello ^a   Rosato, Antonio ^a   Vitali, Cesare ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

Antibacterial activity; Isatin derivatives; Norfloxacin; Pyridazino 4,3 b indole

Indexed keywords

2 (TERT BUTYL) 3 OXO 3,5 DIHYDRO 2H PYRIDAZINO[4,3 B]INDOLE 4 CARBOXYLIC ACID; 2 METHYL 3 OXO 3,5 DIHYDRO 2H PYRIDAZINO[4,3 B]INDOLE 4 CARBOXYLIC ACID; 3 HYDROXY 5H PYRIDAZINO[4,3 B]INDOLE 4 CARBOXYLIC ACID; 3 OXO 2 [4 (TRIFLUOROMETHOXY)PHENYL] 3,5 DIHYDRO 2H PYRIDAZINO[4,3 B]INDOLE 4 CARBOXYLIC ACID; 8 CYCLOHEXYL 2 (4 BROMOPHENYL) 3 OXO 3,5 DIHYDRO 2H PYRIDAZINO[4,3 B]INDOLE 4 CARBOXYLIC ACID; CARBOXYLIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IN VITRO STUDY; LIPOPHILICITY; NONHUMAN;

ANTI-BACTERIAL AGENTS; CARBOXYLIC ACIDS; INDOLES; MICROBIAL SENSITIVITY TESTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036168958     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(01)01173-9     Document Type: Article

References (9)

1. 2-Aryl-2,5-dihydropyridazino[4,3-b]indol-3(3H)-ones: Novel rigid planar benzodiazepine receptor ligands
2. Structure-activity relationships of 2-aryl-2,5-dihydropyridazino[4,3-b]indol-3(3H)-ones at the benzodiazepine receptor
3. Synthesis and antibacterial activity of 2-aryl-2,5-dihydro-3(3H)-oxo-pyridazino[4,3-b]indole-4-carboxylic acids
4. Sandmeyer isonitrosoacetanilide isatin synthesis
5. Synthesis of aminoquinolone derivatives
6. Novel quinolone derivatives as potent antibacterials