Investigation of the pharmacokinetics of celecoxib by liquid chromatography-mass spectrometry

Biomedical Chromatography

Volumn 16, Issue 1, 2002, Pages 56-60

  Werner, Ulrike ^a,b   Werner, Dierk ^a   Pahl, Andreas ^a   Mundkowski, Ralf ^a   Gillich, Martin ^a   Brune, Kay ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ATMOSPHERIC IONIZATION; ATMOSPHERIC PRESSURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION OF LIQUIDS; MASS SPECTROMETRY;

AREAS UNDER THE CURVES; ATMOSPHERIC PRESSURE CHEMICAL IONIZATION MASS SPECTROMETRY; CELECOXIB; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN PLASMAS; LIMIT OF QUANTIFICATIONS; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; LIQUID-LIQUID EXTRACTION; RETENTION TIME; REVERSED-PHASE HIGH PERFORMANCE;

PHARMACOKINETICS;

CELECOXIB; CYTOCHROME P450 2C9; ROFECOXIB;

ADULT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG STRUCTURE; FEMALE; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; MASS SPECTROMETRY; NORMAL HUMAN; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STANDARD; TIME; VALIDATION PROCESS; VOLUNTEER;

EID: 0036163827     PISSN: 02693879     EISSN: None     Source Type: Journal    
DOI: 10.1002/bmc.115     Document Type: Article

References (5)

1. Celecoxib: A review of its use in osteoarthritis, rheumatoid arthritis and acute pain
2. COX-2 inhibitors
3. TOPFIT 2.0-Pharmacokinetic and Pharmacodynamic Data Analysis System for the PC
4. Determination of celecoxib in human plasma by normal-phase high-performance liquid chromatography with column switching and ultraviolet absorbance detection