Growth inhibitory properties of endothelin-1 in activated human hepatic stellate cells: A cyclic adenosine monophosphate-mediated pathway: Inhibition of both extracellular signal-regulated kinase and c-Jun kinase and upregulation of endothelin B receptors

Journal of Clinical Investigation

Volumn 98, Issue 12, 1996, Pages 2771-2778

  Mallat, Ariane ^a   Préaux, Anne Marie ^a   Serradeil Le Gal, Claudine ^b   Raufaste, Danièle ^b   Gallois, Cyrille ^a   Brenner, David A ^c   Bradham, Cynthia ^c   Maclouf, Jacques ^d   Iourgenko, Vadim ^a   Fouassier, Laura ^a   Dhumeaux, Daniel ^a   Mavier, Philippe ^a   Lotersztajn, Sophie ^a  

^a HENRI MONDOR HOSPITAL   (France)

^b SANOFI   (France)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d HÔPITAL LARIBOISIÈRE   (France)

Author keywords

Fibrosis; Liver; Proliferation; Prostaglandins

Indexed keywords

9 (TETRAHYDRO 2 FURYL)ADENINE; CYCLIC AMP; ENDOTHELIN 1; ENDOTHELIN B RECEPTOR; FORSKOLIN; IBUPROFEN; PROSTACYCLIN; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR; SARAFOTOXIN S6A;

ARTICLE; CELL GROWTH; CONTROLLED STUDY; GROWTH INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPATHOLOGY; INHIBITION KINETICS; LIVER CELL; LIVER DISEASE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STELLATE CELL;

ADENYLATE CYCLASE; ADIPOCYTES; BINDING SITES; CELL DIVISION; CELLS, CULTURED; CYCLIC AMP; ENDOTHELIN-1; EPOPROSTENOL; FORSKOLIN; GENES, JUN; HUMANS; IBUPROFEN; LIVER; PROSTAGLANDINS; PROTEIN KINASES; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; RNA, MESSENGER; UP-REGULATION; VIPER VENOMS;

EID: 3142635537     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119103     Document Type: Article

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