Anti-malarial activity of N6-substituted adenosine derivatives. Part I

Bioorganic and Medicinal Chemistry

Volumn 10, Issue 3, 2002, Pages 769-777

  Golisade, Abolfasl ^a   Wiesner, Jochen ^b   Herforth, Claudia ^a   Jomaa, Hassan ^b   Link, Andreas ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

^b Jomaa Pharmaka GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 (6 CHLORO PURIN 9 YL) BETA DEXTRO 1 DEOXYRIBOFURANOSE; ADENOSINE DERIVATIVE; AMINE; N 6 (2,4 DIMETHOXYBENZYL)ADENOSINE; N 6 (3,5 DIFLUOROBENZYL)ADENOSINE; N 6 (3,6 DIOXA 8 AMINOOCTYL)ADENOSINE; N 6 [(2 BIOTINYLAMIDO)ETHYL]ADENOSINE; N 6 [(4 PHENYL)BENZYL]ADENOSINE; N 6 [2 (3 FLUORO 4 METHYLBENZAMIDO)ETHYL]ADENOSINE; N 6 [2 (3 METHOXYBENZAMIDO)ETHYL]ADENOSINE; N 6 [2 (3,3 DIMETHYLACRYLAMIDO)ETHYL]ADENOSINE; N 6 [2 (3,5 DICHLOROBENZAMIDO)ETHYL]ADENOSINE; N 6 [2 [(3 INDOLYL)BUTANAMIDO]ETHYL]ADENOSINE; N 6 [2 [(3 INDOLYL)PROPANAMIDO]ETHYL]ADENOSINE; N 6 [2 [(3 THIENYL)ACETAMIDO]ETHYL]ADENOSINE; N 6 [2 [4 (3 THIENYL)BUTANAMIDO]ETHYL]ADENOSINE; N 6 [2 [4 (N ETHYL N BENZYLAMINO) 3 NITROBENZAMIDO]ETHYL]ADENOSINE; N 6 [2 [4 OXO 4 [(4 PHENYL)PHENYL]BUTANAMIDO]ETHYL]ADENOSINE; N 6 [3,6 DIOXA 8 (1 NAPHTHOXY)OCTYL]ADENOSINE; N 6 [3,6 DIOXA 8 [3 (3 INDOLYL)PROPANAMIDO)OCTYL]ADENOSINE; N 6 [3,6 DIOXA 8 [4 (3 INDOLYL)BUTANAMIDO)OCTYL]ADENOSINE; N 6 [3,6 DIOXA 8 [4 (3 THIENYL)BUTYRAMIDO)OCTYL]ADENOSINE; N 6 [3,6 DIOXA 8 [4 OXO 4 [(4 PHENYL)PHENYL]BUTANAMIDO]OCTYL]ADENOSINE; POLYMER; UNCLASSIFIED DRUG; UNINDEXED DRUG; ADENOSINE; ANTIMALARIAL AGENT; DRUG DERIVATIVE;

ANTIMALARIAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL CULTURE; CONTROLLED STUDY; DERIVATIZATION; DIAGNOSTIC PROCEDURE; DRUG SYNTHESIS; EVALUATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLASMODIUM FALCIPARUM; PROTON NUCLEAR MAGNETIC RESONANCE; THIN LAYER CHROMATOGRAPHY; ANIMAL; CHEMISTRY; COMBINATORIAL CHEMISTRY; DRUG EFFECT; ERYTHROCYTE; GROWTH, DEVELOPMENT AND AGING; HUMAN; IC 50; METHODOLOGY; MICROBIOLOGY; SYNTHESIS;

PLASMODIUM FALCIPARUM;

ADENOSINE; AMINES; ANIMALS; ANTIMALARIALS; COMBINATORIAL CHEMISTRY TECHNIQUES; ERYTHROCYTES; HUMANS; INHIBITORY CONCENTRATION 50; PLASMODIUM FALCIPARUM;

EID: 0036155367     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(01)00331-5     Document Type: Article

References (15)