Blockade of bradykinin B2 receptor suppresses acute pancreatitis induced by obstruction of the pancreaticobiliary duct in rats

British Journal of Pharmacology

Volumn 135, Issue 1, 2002, Pages 29-36

  Hirata, Mitsuhiro ^a   Hayashi, Izumi ^a,b   Yoshimura, Kuniko ^a   Ishii, Ken Ichiro ^a   Soma, Kazui ^a   Ohwada, Takashi ^a   Kakita, Akira ^a   Majima, Masataka ^a,b  

^a KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KITASATO UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

Bradykinin antagonist; Brown Norway Katholiek; FR173657; Hoe140; Oedema; Pancreaticobiliary duct; Pancreatitis

Indexed keywords

3 (6 ACETAMIDO 3 PYRIDYL) N [N [2,4 DICHLORO 3 [(2 METHYL 8 QUINOLINYL)OXYMETHYL]PHENYL] N METHYLAMINOCARBONYLMETHYL]ACRYLAMIDE; AMYLASE; BRADYKININ; BRADYKININ B2 RECEPTOR ANTAGONIST; BRADYKININ[1-5]; GABEXATE MESILATE; ICATIBANT; INDOMETACIN; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ACINAR CELL; ACUTE PANCREATITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT LIGATION; CELL STRUCTURE; COMMON BILE DUCT; CONTROLLED STUDY; DRUG MECHANISM; EDEMA; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; MICROSCOPY; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; RAT; RAT STRAIN; RECEPTOR BLOCKING; STRAIN DIFFERENCE; WATER CONTENT;

ACUTE DISEASE; AMYLASES; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BILE DUCTS; BRADYKININ; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; KININOGENS; LIPASE; MALE; PANCREAS; PANCREATIC DUCTS; PANCREATITIS; PEPTIDE FRAGMENTS; QUINOLINES; RATS; RATS, INBRED STRAINS; RATS, SPRAGUE-DAWLEY; RECEPTOR, BRADYKININ B2; RECEPTORS, BRADYKININ; WATER;

EID: 0036155284     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704462     Document Type: Article

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