Pharmacokinetics of organic anions in rats with arterial calcinosis

Clinical and Experimental Pharmacology and Physiology

Volumn 29, Issue 1-2, 2002, Pages 48-52

  Quaglia, Nora B ^a   Hofer, Claudio G ^a   Torres, Adriana M ^a,b  

^a UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

^b Conicet ^*  (Argentina)

Author keywords

Arterial calcinosis; Organic anions; Pharmacokinetics; Systemic clearance; Vitamin D3

Indexed keywords

ANION; ASPARTATE AMINOTRANSFERASE; BROMSULFOPHTHALEIN; CALCIUM; COLECALCIFEROL; ORGANIC COMPOUND; SULFANILAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CALCIFICATION; ARTICLE; BILIARY EXCRETION; CALCIUM METABOLISM; CONTROLLED STUDY; DRUG CLEARANCE; DRUG ELIMINATION; ENZYME ACTIVITY; EXPERIMENTAL MODEL; HEPATIC ARTERY; LIVER BLOOD FLOW; LIVER LEVEL; MALE; NONHUMAN; RAT; URINARY EXCRETION; VITAMIN D INTOXICATION;

ANIMALS; ANIONS; AORTA, ABDOMINAL; ARTERIAL OCCLUSIVE DISEASES; CALCINOSIS; CHOLECALCIFEROL; KIDNEY; LIVER; MALE; PHENOLSULFONPHTHALEIN; RATS; RATS, WISTAR; SULFANILAMIDES;

EID: 0036153488     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.2002.03604.x     Document Type: Article

References (26)

1. The role of calcium in the pathogenesis of experimental arteriosclerosis
2. Antihypertensive and arterial anticalcinotic effects of calcium antagonists
3. The consequences of aortic calcium overload following vitamin D3 plus nicotine treatment in young rats
4. Role of calcium in arteriosclerosis: Experimental evaluation of antiarteriosclerotic potencies of Ca antagonists
5. Additional evidence for the binding of calcium ions to elastin at neutral sites
6. Molecular pharmacology of organic anion transporters
7. Hepatic transport of drugs and proteins
8. Drug dosing in renal insufficiency
9. Interrelationships between excretion of drugs via urine and bile
10. Difference in the hepatic uptake of tetra- and dibromosulfophthalein: Role of hydrophobicity, binding to plasma proteins and affinity for plasma membrane carrier protein
11. Gender differential liver plasma membrane affinities in tetra-bromosulfonephthalein in hepatic uptake
12. Hepatic organic anion uptake in the rat
13. Influence of obesity on sulfonamide disposition in Zucker rats
14. PKCALC: A basic interactive computer program for statistical and pharmacokinetic analysis of data
15. Using nonlinear regression to fit curves
16. A new coupling reagent for sulfanilamide determination
17. Decrease in endothelium-dependent relaxation in the mesenteric arterial bed following vascular calcium overload produced by vitamin D3 and nicotine in rats
18. Calcium antagonism and ACE inhibition: Two outstanding effective means of interference with cardiovascular calcium overload, high blood pressure, and arteriosclerosis in spontaneously hypertensive rats
19. Biliary transport and hepatic storage of sulfobromophthalein
20. 1,25-Dihydroxyvitamin D stimulates sodium-dependent phosphate transport by renal outer cortical brush border membrane vesicles by directly affecting membrane fluidity
21. Effect of 1,25-dihydroxyvitamin D3 on phospholipid composition of rat renal brush border membrane
22. Role of vitamin D3 on the activity patterns of hepatic drug metabolizing enzymes in transplantable murine lymphoma
23. 2 vitamin D enhances resistance artery contractile properties
24. Modulation of lyso-platelet-activating factor: Acetyl-CoA acetyltransferase from rat splenic microsomes. The role of calcium ions