Newborns and gentamicin - How much and how often?

Journal of Antimicrobial Chemotherapy

Volumn 49, Issue 1, 2002, Pages 13-16

  Chattopadhyay, B ^a  

^a BARTS HEALTH NHS TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; BETA LACTAM ANTIBIOTIC; CREATININE; GENTAMICIN;

ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL INFECTION; BACTERICIDAL ACTIVITY; BIRTH WEIGHT; CLINICAL PROTOCOL; COAGULASE NEGATIVE STAPHYLOCOCCUS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; CREATININE BLOOD LEVEL; DISTRIBUTION VOLUME; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG COST; DRUG EFFECT; DRUG ELIMINATION; DRUG HALF LIFE; DRUG MONITORING; DRUG POTENTIATION; DRUG USE; GESTATIONAL AGE; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY FUNCTION; NEPHROTOXICITY; NEWBORN; NEWBORN CARE; NONHUMAN; OTOTOXICITY; PRACTICE GUIDELINE; PREDICTION; REGRESSION ANALYSIS; STANDARDIZATION;

EID: 0036151597     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/49.1.13     Document Type: Article

References (53)

1. Aminoglycoside toxicity - A review of clinical studies published between 1975 and 1982
2. Urinary enzyme activity in children and neonates receiving gentamicin therapy
3. Aminoglycoside-related nephrotoxicity in the premature newborn
4. Aminoglycosides and neonatal deafness
5. Evaluation of gentamicin pharmacokinetics and dosing protocols in 195 neonates
6. Gentamicin dosage in pre-term and term neonates
7. Monitoring serum levels of gentamicin to develop a new regimen for gentamicin dosage in newborns
8. Effectiveness of a gentamicin dosing protocol based on post-conceptional age: Comparison to published neonatal guidelines
9. Population pharmacokinetics of gentamicin in premature infants
10. Pharmacokinetics and antibacterial activity of daily gentamicin
11. Ototoxicity of gentamicin in man: A survey and controlled analysis of clinical experience in the United States
12. Evaluation of gentamicin therapy in newborns at a community hospital and development of simple dosing guidelines
13. Incidence of potentially toxic concentrations of gentamicin in the neonates
14. Post-conceptional age and gentamicin elimination half-life
15. Kinetic model for gentamicin dosing with the use of individual patient parameters
16. Pharmacokinetics of gentamicin in very low birth weight preterm infants
17. Antimicrobial Therapy for Newborns
18. Relationship of gentamicin serum concentrations to gestational age in preterm and term neonates
19. Two-compartment gentamicin pharmacokinetics in neonates: A comparison to adults with decreased glomerular filtration rates
20. Optimization of gentamicin therapy in very low birth weight infants
21. Population pharmacokinetics of gentamicin in neonates
22. Gentamicin kinetics in the neonate
23. Developmental pharmacokinetics of gentamicin in neonates: Relationship to post-conceptional age and renal function
24. Developmental patterns of renal functional maturation compared in the human neonate
25. Insulin clearance in the newborn infant: Relationship to gestational age and postnatal age
26. Once-daily gentamicin dosing in newborn infants
27. The kinetic profile of gentamicin in premature neonates
28. A multicentre evaluation of gentamicin therapy in the neonatal intensive care unit
29. Use of higher dose extended interval aminoglycosides in a neonatal intensive care unit
30. Gentamicin interval in newborn infants as determined by renal function and post-conceptional age
31. Urinary excretion of gentamicin in the neonatal period
32. Pharmacologic evaluation of gentamicin in newborn infants
33. Limitations on the physiologic interpretation of aminoglycoside body clearance derived from pharmacokinetic studies
34. A simple method for the estimation of glomerular filtration rate by gentamicin pharmacokinetics during routine monitoring in the newborn
35. Predictors of trough serum gentamicin concentrations in neonates
36. Reliability of plasma creatinine measurement in children
37. Gentamicin disposition and the effect on development in the very low birth weight infant
38. Gentamicin monitoring in neonates
39. Effectiveness and toxicity of gentamicin in an experimental model of pyelonephritis: Effect of the time of administration
40. Ceftriaxone-netilmicin combination in single-daily-dose treatment of experimental Escherichia coli endocarditis
41. Synergistic activity of ceftriaxone combined with netilmicin administered once daily for treatment of experimental streptococcal endocarditis
42. A meta-analysis of the relative efficacy and toxicity of single daily dosing of aminoglycosides
43. A meta-analysis of extended-interval dosing versus multiple daily dosing of aminoglycosides
44. Single or multiple daily dosing of aminoglycosides: A meta analysis
45. Effectiveness and safety of once-daily aminoglycosides: A meta analysis
46. Aminoglycosides: Single or multiple daily dosing? A meta-analysis on efficacy and safety
47. Once-daily aminoglycoside dosing in immunocompetent adults: A meta-analysis
48. A meta-analysis of studies on the safety and efficacy of aminoglycosides given either once daily or as divided doses
49. Circadian variations in serum levels and the renal toxicity of aminoglycosides in patients
50. Standard gentamicin dosage regimen in neonates
51. Population pharmacokinetics of gentamicin in pre term neonates: Evaluation of a once-daily dosage regimen