The structure of spider toxin huwentoxin-II with unique disulfide linkage: Evidence for structural evolution

Protein Science

Volumn 11, Issue 2, 2002, Pages 245-252

  Shu, Qin ^a   Lu, Shan Yun ^a   Gu, Xiao Cheng ^a   Liang, Song Ping ^b  

^a PEKING UNIVERSITY   (China)

^b HUNAN NORMAL UNIVERSITY   (China)

Author keywords

Disulfide bond; Disulfide directed hairpin; Huwentoxin II; Inhibitor cystine knot motif; Spider toxin; Three dimensional structure; Two dimensional NMR

Indexed keywords

CYSTINE; HUWENTOXIN II; INSECTICIDE; PEPTIDE; SPIDER VENOM; UNCLASSIFIED DRUG;

ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; CROSS LINKING; DISULFIDE BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; PROTON NUCLEAR MAGNETIC RESONANCE; SPIDER; TOXIN STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; DISULFIDES; EVOLUTION, MOLECULAR; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEUROTOXINS; PROTEIN CONFORMATION; PROTEIN FOLDING; SEQUENCE HOMOLOGY, AMINO ACID; SPIDER VENOMS; SPIDERS;

ARANEAE; INVERTEBRATA; ORNITHOCTONUS HUWENA;

EID: 0036147845     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.30502     Document Type: Article

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