Flexibility and function in HIV protease: Dynamics of the HIV-1 protease bound to the asymmetric inhibitor kynostatin 272 (KNI-272)

Journal of the American Chemical Society

Volumn 120, Issue 31, 1998, Pages 7916-7923

  Freedberg, Darón I ^a   Wang, Yun Xing ^a   Stahl, Stephen J ^b   Kaufman, Joshua D ^b   Wingfield, Paul T ^b   Kiso, Yoshiaki ^c   Torchia, Dennis A ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^c KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN IMMUNODEFOCIENCY VIRUS 1 PROTEINASE; KYNOSTATIN 272; PROTEINASE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; DRUG BINDING; ENZYME ACTIVITY; ENZYME ASSAY; HUMAN IMMUNODEFICIENCY VIRUS; LIGAND BINDING; MATHEMATICAL ANALYSIS; PROTEINASE INHIBITION; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS;

EID: 0032511368     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja981206r     Document Type: Article

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