Tissue transglutaminase localization and activity regulation in the extracellular matrix of articular cartilage

Journal of Orthopaedic Research

Volumn 20, Issue 1, 2002, Pages 76-82

  Summey Jr , Brett T ^a   Graff, Ronald D ^a   Lai, Thung Sheng ^b   Greenberg, Charles S ^b   Lee, Greta M ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CATALYST ACTIVITY; CROSSLINKING; ENZYMES; IMMUNOLOGY; PROTEINS;

IMMUNOREACTIVITIES;

CARTILAGE;

CADAVERINE; CALCIUM ION; FLUORESCEIN; GUANOSINE TRIPHOSPHATE; MAGNESIUM ION; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

ADULT; AGED; ANTIBODY LABELING; ARTICLE; ARTICULAR CARTILAGE; CATALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ASSAY; ENZYME REGULATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; KNEE OSTEOARTHRITIS; MECHANICAL STRESS; PRIORITY JOURNAL; PROTEIN CROSS LINKING; TISSUE DISTRIBUTION; TOTAL KNEE REPLACEMENT;

EID: 0036145043     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0736-0266(01)00064-X     Document Type: Article

References (30)

1. Identification of a guanosine triphosphate-binding site on guinea pig liver transglutaminase. Role of GTP and calcium ions in modulating activity
2. Tissue transglutaminase and factor XIII in cartilage and bone remodeling
3. Transglutaminases: Protein cross-linking enzymes in tissues and body fluids
4. Expression of tissue transglutaminase in skeletal tissues correlates with events of terminal differentiation of chondrocytes
5. Induction of tissue transglutaminase in HIV pathogenesis: Evidence for high rate of apoptosis of CD4+ T lymphocytes and accessory cells in lymphoid tissues
6. Inhibition of erythrocyte transglutaminase by GTP
7. A monoclonal antibody to cellular transglutaminase
8. Cartilage fibronectin isoforms: In search of functions for a special population of matrix glycoproteins
9. Two types of transglutaminase in the PC12 pheochromocytoma cell line. Stimulation by sodium butyrate
10. Retinoids induce tissue transglutaminase in NIH-3T3 cells
11. Transglutaminase activity in rabbit articular chondrocytes in culture
12. A transglutaminase that converts interleukin-2 into a factor cytotoxic to oligodendrocytes
13. Studies of thrombin-induced proteoglycan release in the degradation of human and bovine cartilage
14. Expression of tissue transglutaminase in Balb-C 3T3 fibroblasts: Effects on cellular morphology and adhesion
15. ATP release by mechanically loaded chondrons in pellet culture
16. Interconversion of extracellular nucleotides by ectonucleoside diphosphokinase on porcine articular chondrocytes
17. Transglutaminases: Multifunctional cross-linking enzymes that stabilize tissues
18. Release, metabolism and interconversion of adenine and uridine nucleotides: Implications for G protein-coupled P2 receptor agonist selectivity
19. GTP binding and signaling by Gh/transglutaminase II involves distinct residues in a unique GTP-binding pocket
20. Promotion of thrombin-catalyzed activation of factor XIII by fibrinogen
21. Transfection of tissue transglutaminase into a highly malignant hamster fibrosarcoma leads to a reduced incidence of primary tumour growth
22. Regulation of human tissue transglutaminase function by magnesium-nucleotide complexes. Identification of distinct binding sites for Mg-GTP and Mg-ATP
23. Detection and characterization, using fluoresceincadaverine, of amine acceptor protein substrates accessible to active transglutaminase expressed by rabbit articular chondrocytes
24. Quantitation of extracellular UTP using a sensitive enzymatic assay
25. Identification of an ecto-nucleoside diphosphokinase and its contribution to interconversion of P2 receptor agonists
26. Tissue transglutaminase and apoptosis: Sense and antisense transfection studies with human neuroblastoma cells
27. Cross-linking of the dermo-epidermal junction of skin regenerating from keratinocyte autografts. Anchoring fibrils are a target for tissue transglutaminase
28. Transglutaminase activity in aging articular chondrocytes and articular cartilage vesicles
29. Physiological concentrations of purines and pyrimidines
30. Modulation of the in situ activity of tissue transglutaminase by calcium and GTP