Somatostatin is a selective chemoattractant for primitive (CD34+) hematopoietic progenitor cells

Experimental Hematology

Volumn 30, Issue 2, 2002, Pages 116-125

  Oomen, Sigrid P M A ^a   Van Hennik, Paula B ^a   Antonissen, Claudia ^a   Lichtenauer Kaligis, Elgin G R ^a   Hofland, Leo J ^a   Lamberts, Steven W J ^a   Löwenberg, Bob ^a   Touw, Ivo P ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BUCLADESINE; CD34 ANTIGEN; CHEMOATTRACTANT; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; OCTREOTIDE; PEPTIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE INHIBITOR; RECEPTOR SUBTYPE; REGULATOR PROTEIN; SOMATOSTATIN; SOMATOSTATIN 14; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR; STROMAL CELL DERIVED FACTOR 1; SYNAPTOPHYSIN; WORTMANNIN;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL MIGRATION; CELL TYPE; CONTROLLED STUDY; DRUG MECHANISM; FLOW CYTOMETRY; GENETIC TRANSFECTION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD34; CHEMOTAXIS; COLONY-FORMING UNITS ASSAY; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HORMONES; HUMANS; MEMBRANE PROTEINS; MICE; RECEPTORS, SOMATOSTATIN; SOMATOSTATIN;

EID: 0036144729     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(01)00772-X     Document Type: Article

References (64)

1. Stromal cells in haemopoiesis
2. The role of growth factors in self-renewal and differentiation of haemopoietic stem cells
3. Cell adhesion in the stromal regulation of haemopoiesis
4. Biology of the hemopoietic microenvironment
5. Ultrastructural morphometric study of efferent nerve terminals on murine bone marrow stromal cells, and the recognition of a novel anatomical unit; the 'neuro-reticular complex'
6. Bone marrow innervation regulates cellular retention in the murine haemopoietic system
7. Coordinated host defense through an integration of the neural, immune and haemopoietic systems
8. Neuropeptide control of bone marrow neutrophil production is mediated by both direct and indirect effects on CFU-GM
9. Nerve growth factor induces development of connective tissue-type mast cells in vitro from murine bone marrow cells
10. 2.5S nerve growth factor enhances survival, phagocytosis, and superoxide production of murine neutrophils
11. The somatostatin receptor family
12. Somatostatin
13. Octreotide
14. Somatostatin analogue scintigraphy of malignant lymphomas
15. Somatostatin and its cyclic octapeptide analog SMS 201-995 as inhibitors of proliferation of human acute lymphoblastic and acute myeloid leukemia
16. Somatostatin receptors on human lymphocytes and leukaemia cells
17. Calcitonin and somatostatin immunoreactive cells are present in human bone marrow and bone marrow cells are responsive to calcitonin and somatostatin
18. Differential internalization of somatostatin in COS-7 cells transfected with SST1 and SST2 receptor subtypes; a confocal microscopic study using novel fluorescent somatostatin derivatives
19. Agonist-dependent regulation of cloned human somatostatin receptor types 1-5 (hSSTR1-5); subtype selective internalization or upregulation
20. The cytoplasmic tail of the human somatostatin receptor type 5 is crucial for interaction with adenylyl cyclase and in mediating desensitization and internalization
21. Somatostatin and its receptor family
22. Chemokines and leukocyte traffic
23. + progenitors to peripheral blood
24. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1) (see comments)
25. Stimulating spectrum of human recombinant multi-CSF (IL-3) on human marrow precursors; importance of accessory cells
26. 4-Hydroperoxycyclophosphamide purging of breast cancer from the mononuclear cell fraction of bone marrow in patients receiving high-dose chemotherapy and autologous marrow support; a phase I trial
27. Somatostatin receptor subtype 2 knockout mice are refractory to growth hormone-negative feedback on arcuate neurons
28. Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions
29. In vitro characterization of somatostatin receptors in the human thymus and effects of somatostatin and octreotide on cultured thymic epithelial cells
30. An attempt to produce 'pre-T' cell hybridomas and to identify their antigens
31. Murine macrophage precursor characterization. II. Monoclonal antibodies against macrophage precursor antigens
32. Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cells
33. Mac-1; a macrophage differentiation antigen identified by monoclonal antibody
34. A monoclonal antibody that recognizes B cells and B-cell precursors in mice
35. In utero manipulation of coat color formation by a monoclonal anti-c- kit antibody; two distinct waves of c-kit dependency during melanocyte development
36. Mutations in the gene for the granulocyte colony-stimulating factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia (see comments)
37. Advanced mammalian gene transfer; high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
38. Multiple signals mediate proliferation, differentiation, and survival from the granulocyte colony-stimulating factor receptor in myeloid 32D cells
39. Growth inhibitory effects of somatostatin on human leukemia cell lines mediated by somatostatin receptor subtype 1
40. c-Raf-mediated inhibition of epidermal growth factor-stimulated cell migration
41. A role for p38(MAPK)/HSP27 pathway in smooth muscle cell migration
42. Comparison of the roles of mitogen-activated protein kinase kinase and phosphatidylinositol 3-kinase signal transduction in neutrophil effector function
43. Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinases
44. Phosphoinositide kinases
45. An 11-amino acid sequence from c-met initiates epithelial chemotaxis via phosphatidylinositol 3-kinase and phospholipase C
46. Regulation of chemotaxis by the platelet-derived growth factor receptor-β
47. PI 3-kinase-dependent and independent chemotaxis of human neutrophil leukocytes
48. Subunits β γ of heterotrimeric G protein activate β 2 isoform of phospholipase C
49. A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation
50. Cell migration; a physically integrated molecular process
51. Actin-based cell motility and cell locomotion
52. The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts
53. Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
54. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
55. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
56. Somatostatin acts by inhibiting the cyclic 3′,5′-adenosine monophosphate (cAMP)/protein kinase A pathway, cAMP response element-binding protein (CREB) phosphorylation, and CREB transcription potency
57. Leukocyte polarization in cell migration and immune interactions
58. A cell's sense of direction
59. Chemoattractant receptor cross-desensitization
60. The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract
61. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development (see comments)
62. An in vitro limiting-dilution assay of long-term repopulating hematopoietic stem cells in the mouse
63. Expression patterns of rat somatostatin receptor genes in pre- and postnatal brain and pituitary
64. Identification of somatostatin receptor subtypes and an implication for the efficacy of somatostatin analogue SMS 201-995 in treatment of human endocrine tumors