Effects of intracoronary calcium chloride on regional oxygen balance and mechanical function in normal and stunned myocardium in dogs

British Journal of Anaesthesia

Volumn 88, Issue 1, 2002, Pages 78-86

  Yoo, K Y ^a   Lee, J U ^b   Kwak, S H ^a   Im, W M ^a   Jeong, C Y ^a   Chung, S S ^a   Yoon, M H ^a   Jeong, S W ^a   Park, J T ^b  

^a Chonnam National University Medical School   (South Korea)

^b Chonnam National University   (South Korea)

Author keywords

Dog; Drugs, inotropic; Heart, coronary circulation; Ions, calcium

Indexed keywords

CALCIUM CHLORIDE; ENFLURANE; FENTANYL; LACTIC ACID; MIDAZOLAM; OXYGEN; THIOPENTAL; VECURONIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCULATION; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY CONSTRICTION; DOG; DOSE RESPONSE; DRUG EFFECT; DRUG RESPONSE; ENDOTHELIUM LESION; FEMALE; HEART FUNCTION; HEART MUSCLE ISCHEMIA; HEART MUSCLE OXYGEN CONSUMPTION; HEART MUSCLE REPERFUSION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NONHUMAN; PRIORITY JOURNAL; STUNNED HEART MUSCLE; ULTRASOUND TRANSDUCER;

EID: 0036139922     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/88.1.78     Document Type: Article

References (35)

1. The stunned myocardium: Prolonged, postischemic ventricular dysfunction
2. Postischemic myocardial 'stunning': A clinically relevant phenomenon
3. Reversibly injured, postischemic canine myocardium retains normal contractile reserve
4. Effects of intracoronary calcium chloride on the postischemic heart in pigs
5. Responses of blood flow, oxygen consumption, and contractile function to inotropic stimulation in stunned canine myocardium
6. A randomized, blinded, placebo-controlled evaluation of calcium chloride and epinephrine for inotropic support after emergence from cardiopulmonary bypass
7. The effect of adrenaline upon the coronary circulation
8. Is calcium a coronary vasoconstrictor in vivo?
9. Functional coronary microvascular injury evident as increased permeability due to brief ischemia and reperfusion
10. Brief ischemia-reperfusion induces stunning of endothelium in canine coronary artery
11. Increased oxygen cost of contractility in stunned myocardium of dog
12. 2+ activation of contraction as a consequence of reperfusion induced cellular calcium overload in ferret hearts
13. Effects of calcium chloride administration on the postischemic isolated rat heart
14. Validation of local venous sampling within the at risk left anterior vascular bed in the canine left ventricle
15. Regional myocardial function and dimensions early and late after myocardial infarction in the unanesthetized dog
16. Inotropic response of stunned hypertrophied myocardium: Responsiveness of hypertrophied and normal postischemic isolated rat hearts to calcium and dopamine stimulation
17. Calcium responsiveness in regional myocardial short-term hibernation and stunning in the in situ porcine heart: Inotropic responses to postextrasystolic potentiation and intra-coronary calcium
18. Decreased myofilament responsiveness in myocardial stunning follows transient calcium overload during ischemia and reperfusion
19. Halothane decreases calcium sensitivity of rat aortic smooth muscle
20. The direct effects of enflurane on coronary blood flow, myocardial oxygen consumption, and myocardial segmental shortening in in situ canine hearts
21. Regional asynchrony of segmental contraction may explain the 'oxygen consumption paradox' in stunned myocardium
22. Effect of inotropic stimulation on the synchrony of left ventricular wall motion in a dog model of myocardial stunning
23. Effects and interactions of myocardial ischaemia and alterations in circulating blood volume on canine left ventricular diastolic function
24. 2+ responsiveness and altered diastolic function in intact ventricular muscle
25. Effects of calcium on left ventricular function early after cardiopulmonary bypass
26. Lack of direct role for calcium in ischaemic diastolic dysfunction in isolated hearts
27. Hemodynamic effects of calcium chloride injection following cardiopulmonary bypass: Response to bolus injection and continuous infusion
28. Ionized calcium, the heart, and hemodynamic function
29. Hemodynamic effects of calcium chloride administered intravenously to patients with and without cardiac disease during neurolept anaesthesia
30. Myocardial lactate extraction: Multidetermined metabolic function
31. Myocardial oxygen consumption, oxygen supply/demand heterogeneity, and microvascular patency in regionally stunned myocardium
32. Low-dose dobutamine echocardiography detects reversible dysfunction after thrombolytic therapy of acute myocardial infarction
33. Recovery of contractile function of stunned myocardium in chronically instrumented dogs is enhanced by halothane or isoflurane
34. Calcium preconditioning in human myocardium
35. Effects of halothane and isoflurane on postischemic 'stunned' myocardium in the dog