The direct effects of enflurane on coronary blood flow, myocardial oxygen consumption, and myocardial segmental shortening in in situ canine hearts

Anesthesia and Analgesia

Volumn 83, Issue 1, 1996, Pages 68-74

  Gurevicius, Juozas ^b   Holmes, Charles B ^b   Salem, M Ramez ^b   Abdel Halim, Ayman ^b   Crystal, George J ^a  

^a ADVOCATE ILLINOIS MASONIC MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ENFLURANE; FENTANYL; HALOTHANE; ISOFLURANE; LACTIC ACID; MIDAZOLAM; THIOPENTAL; VECURONIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DILATATION; DOG; DRUG BLOOD LEVEL; EXTRACORPOREAL CIRCULATION; FEMALE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE OXYGEN CONSUMPTION; INOTROPISM; INTRAARTERIAL DRUG ADMINISTRATION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NONHUMAN; PRIORITY JOURNAL;

ANESTHETICS, INHALATION; ANIMALS; CORONARY CIRCULATION; DOGS; ENFLURANE; FEMALE; HEART; MALE; MYOCARDIUM; OXYGEN CONSUMPTION;

EID: 0029900550     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-199607000-00012     Document Type: Article

References (25)

1. Feigl EO. Coronary physiology. Physiol Rev 1983;63:1-205.
2. Pagel PS, Kampine JP, Schmelling WT, Warltier DC. Comparison of systemic and coronary hemodynamic actions of desflurane, isoflurane, halothane, and enflurane in chronically instrumented dog. Anesthesiology 1991;74:539-51.
3. Hysing ES, Chelly JE, Doursout M-F, Merin RG. Comparative effects of halothane, enflurane and isoflurane at equihypotensive doses on cardiac performance and coronary and renal blood flows in chronically instrumented dogs. Anesthesiology 1992;76:979-84.
4. Merin RG, Kumazawa T, Luka NL. Enflurane depresses myocardial function, perfusion, and metabolism in the dog. Anesthesiology 1976;45:501-7.
5. Stowe DF, Marijic J, Bosnjak ZJ, Kampine JP. Direct comparative effects of halothane, enflurane, and isoflurane on oxygen supply and demand in isolated hearts. Anesthesiology 1991;74:1087-95.
6. Sahlman L, Henriksson B-A, Martner J, Ricksten S-E. Effects of halothane, enflurane, and isoflurane on coronary vascular tone, myocardial performance, and oxygen consumption during controlled changes in aortic and left atrial pressure. Anesthesiology 1988;69:1-10.
7. Crystal GJ, Khoury E, Gurevicius J, Salem MR. Direct effects of halothane on coronary blood flow, myocardial oxygen consumption, and myocardial segmental shortening in in situ canine hearts. Anesth Analg 1995;80:256-62.
8. Crystal GJ, Kim S-J, Czinn EA, et al. Intracoronary isoflurane causes marked vasodilation in canine hearts. Anesthesiology 1991;74:757-65.
9. Vinten-Johansen J, Johnson WE, Crystal GJ, et al. Validation of local venous sampling within the at risk left anterior vascular bed in canine left ventricle. Cardiovasc Res 1987;21:646-51.
10. Roberts DL, Nakazawa HK, Klocke FJ. Origin of great cardiac vein and coronary sinus drainage within the left ventricle. Am J Physiol 1976;230:480-92.
11. Crystal GJ, Salem MR. Myocardial oxygen consumption and segmental shortening during selective coronary hemodilution in dogs. Anesth Analg 1988;67:500-8.
12. Streeter DD, Spotnitz HM, Patel DP, et al. Fiber orientation in the canine left ventricle during diastole and systole. Circ Res 1969;40:158-65. ;
13. Lange R, Ware J, Kloner RA. Absence of cumulative deterioration of regional function during three repeated 5 or 15 minutes coronary occlusions. Circulation 1984;69:400-8.
14. Yamamura H, Waskasugi B, Sato S, Takebe Y. Gas chromatographic analysis of inhalational anesthetics in whole blood by an equilibration method. Anesthesiology 1966;27:311-7.
15. Gurevicius J, Salem MR, Metwally AA, et al. Contribution of nitric oxide to coronary vasodilation during hypercapnic acidosis. Am J Physiol 1995;268:H39-47.
16. Eger EI II. Uptake of inhaled anesthetics: the alveolar to inspired anesthesia difference. Anesthetic uptake and action. 4th ed. Baltimore: Williams & Wilkins, 1976:77-96.
17. Zar JH. Biostatistical analysis. Englewood Cliffs, NJ: Prentice-Hall, 1974.
18. Crystal GJ, Czinn EA, Silver JM, Salem MR. Coronary vasodilation by isoflurane: abrupt vs. gradual administration. Anesthesiology 1995;82:542-9.
19. Crystal GJ, Kim S-J, Salem MR, et al. Nitric oxide does not mediate coronary vasodilation by isoflurane. Anesthesiology 1994;81:209-20.
20. Gayheart PA, Vinten-Johansen J, Johnston WE, et al. Oxygen requirements of the dyskinetic myocardial segment. Am J Physiol 1989;257:H1184-91.
21. Scheuer J, Brachfield N. Coronary insufficiency: relations between hemodynamic, electrical, and biochemical parameters, Circ Res 1966;18:H178-89.
22. Coetzee A, Fourie P. Effect of halothane, enflurane, and isoflurane on the end-systolic pressure-length relationship. Can J Anaesth 1987;34:351-7.
23. Housmans P, Murat I. Comparative effects of halothane, enflurane, and isoflurane at equipotent anesthetic concentrations on isolated ventricular myocardium of the ferret. I. Contractility. Anesthesiology 1988;69:451-63.
24. Merin RG. Are the myocardial functional and metabolic effects of isoflurane really different from those of halothane and enflurane? Anesthesiology 1981;55:398-408.
25. Theroux P, Ross J Jr, Franklin D, et al. Regional myocardial function in the conscious dog during coronary occlusion and responses to morphine, propranolol, nitroglycerin, and lidocaine. Circulation 1976;53:302-14.