Calcium sensitizer EMD 57033, but not the β1-adrenoreceptor agonist dobutamine, increases mechanical efficiency in stunned myocardium

Journal of Cardiovascular Pharmacology

Volumn 39, Issue 1, 2002, Pages 61-72

  Trines, S A I P ^a   Smits, C A G ^a   Van der Moer, J ^a   Slager, C J ^a   Verdouw, P D ^a   Krams, R ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Calcium sensitization; Dobutamine; EMD 57033; Energetics; Mechanical efficiency; Regional myocardial stunning

Indexed keywords

5 [1 (3,4 DIMETHOXYBENZOYL) 1,2,3,4 TETRAHYDRO 4,4 DIMETHYL 6 QUINOLYL] 3,6 DIHYDRO 6 METHYL 1,3,4 THIADIAZIN 2 ONE; 5 [1 (3,4 DIMETHOXYBENZOYL) 1,2,3,4 TETRAHYDRO 6 QUINOLYL] 3,6 DIHYDRO 6 METHYL 2H 1,3,4 THIADIAZIN 2 ONE; DOBUTAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; ENERGY TRANSFER; HEART MUSCLE CONTRACTILITY; HEART MUSCLE OXYGEN CONSUMPTION; HEMODYNAMICS; INOTROPISM; NONHUMAN; PRIORITY JOURNAL; STATISTICAL ANALYSIS; STRESS STRAIN RELATIONSHIP; STUNNED HEART MUSCLE; SWINE;

ADRENERGIC BETA-AGONISTS; ANIMALS; CALCIUM; CARDIOTONIC AGENTS; DOBUTAMINE; ENERGY METABOLISM; HEART; HEMODYNAMIC PROCESSES; MYOCARDIAL CONTRACTION; MYOCARDIAL STUNNING; OXYGEN CONSUMPTION; QUINOLINES; STIMULATION, CHEMICAL; SWINE; THIADIAZINES;

EID: 0036137096     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200201000-00008     Document Type: Article

References (26)

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2. Mechanical efficiency of stunned myocardium is modulated by increased after-load dependency
3. Ventricular stroke work and efficiency both remain nearly optimal despite altered vascular loading
4. Efficiency of energy transfer, but not external work, is maximized in stunned myocardium
5. Ventricular energetics
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18. Missing data in two-way analysis of variance
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