The effect of a thiadiazinone derived Ca2+ sensitizer on the responsiveness of Mg2+-ATPase to Ca2+ in myofibrils isolated from stunned and nonstunned porcine and human myocardium

Biochemical Pharmacology

Volumn 51, Issue 9, 1996, Pages 1211-1220

  Bezstarosti, Karel ^a   Soei, Loe Kie ^a   Krams, Rob ^a   Ten Cate, Folkert J ^a   Verdouw, Pieter D ^a   Lamers, Jos M J ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

Ca2+ stimulated; Cardiac myofibrils; Cardiac sarcoplasmic reticulum; Human; Mg2+ ATPase; Myocardial stunning; Pig; Thiadiazinone derivatives

Indexed keywords

5 [1 (ALPHA ETHYLIMINO 3,4 DIMETHOXYBENZYL) 1,2,3,4 TETRAHYDRO 6 QUINOLINYL] 3,6 DIHYDRO 6 METHYL 2H 1,3,4 THIADIAZIN 2 ONE; ADENOSINE TRIPHOSPHATASE (CALCIUM MAGNESIUM); CALCIUM; THIADIAZINE DERIVATIVE; 5 [1 (3,4 DIMETHOXYBENZOYL) 1,2,3,4 TETRAHYDRO 6 QUINOLYL] 3,6 DIHYDRO 6 METHYL 2H 1,3,4 THIADIAZIN 2 ONE; ADENOSINE TRIPHOSPHATASE (MAGNESIUM); ADENOSINE TRIPHOSPHATASE INHIBITOR; CALCIUM SENSITIZER; THAPSIGARGIN; THIADIAZINONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; BLOOD; CARDIOMEGALY; CELL FRACTIONATION; DRUG EFFECT; ENZYMOLOGY; HEART MUSCLE; HUMAN; IN VITRO STUDY; METABOLISM; MUSCLE FIBRIL; STEREOISOMERISM; SWINE; ANIMAL TISSUE; CARDIOMYOPATHY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG MECHANISM; ENANTIOMER; ENZYME ACTIVITY; HEART HYPERTROPHY; HEART VENTRICLE; HUMAN TISSUE; INOTROPISM; NONHUMAN; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM; STUNNED HEART MUSCLE;

ANIMALS; CA(2+) MG(2+)-ATPASE; CALCIUM; CARDIOMEGALY; HUMANS; MYOCARDIUM; MYOFIBRILS; STEREOISOMERISM; SUBCELLULAR FRACTIONS; SWINE; THIADIAZINES;

EID: 0029926713     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00083-4     Document Type: Article

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