Plasma pharmacokinetics and tissue distribution of a N-pyrrolo[1,2-c]imidazolylphenyl sulfonamide in rats

Drug Metabolism and Disposition

Volumn 30, Issue 1, 2002, Pages 47-54

  Moghaddam, M F ^a   Bogdanffy, M S ^a   Brown, A ^a   Ford, K ^a   Shalaby, L ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 14; DRUG METABOLITE; HERBICIDE; HYDANTOIN; IMIDAZOLE DERIVATIVE; N PYRROLO[1,2 C]IMIDAZOLYLPHENYLSULFONAMIDE; PROTOPORPHYRINOGEN OXIDASE; TY 029; UNCLASSIFIED DRUG;

AGRICULTURE; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CARCASS; CONCENTRATION RESPONSE; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG METABOLISM; ENZYME INHIBITION; FEMALE; GASTROINTESTINAL TRACT; ISOTOPE LABELING; LIVER LEVEL; MALE; MASS SPECTROMETRY; NONHUMAN; PLANT GROWTH; PRIORITY JOURNAL; RAT; SAFETY; TISSUE DISTRIBUTION; TOXICOLOGY;

ANIMALS; CARBON RADIOISOTOPES; FEMALE; HERBICIDES; MALE; PYRROLES; RATS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SULFONAMIDES; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 0036136389     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.30.1.47     Document Type: Article

References (4)

1. Biotransformation of TY029, an experimental herbicide, in rats
2. Effects of phenobarbital on the distribution, pharmacokinetics, and biological half-lives of model non-microsomal enzyme metabolizable sulfonamides in rats