Biotransformation, excretion kinetics, and tissue distribution of an N-pyrrolo[1,2-c]imidazolylphenyl sulfonamide herbicide in rats

Drug Metabolism and Disposition

Volumn 29, Issue 8, 2001, Pages 1162-1170

  Moghaddam, Mehran F ^a   Brown, Alethia ^a   Budevska, Boiana O ^a   Zamas, L A M ^b   Payne, William G ^a  

^a DUPONT COMPANY   (United States)

^b Quest Pharmaceutical Services   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; HERBICIDE; IMIDAZOLE DERIVATIVE; N PYRROLO[1,2 C]IMIDAZOLYLPHENYLSULFONAMIDE; SULFONAMIDE; TY 029; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHIRALITY; DRUG CONJUGATION; DRUG EXCRETION; DRUG EXPOSURE; DRUG TRANSFORMATION; FEEDING; FEMALE; HYDROLYSIS; HYDROXYLATION; MALE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; TISSUE DISTRIBUTION; URINARY EXCRETION;

ANIMALS; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FECES; FEMALE; HERBICIDES; MALE; MASS SPECTROMETRY; PYRROLES; RATS; RATS, INBRED STRAINS; SPECTROPHOTOMETRY, INFRARED; SULFONAMIDES; TISSUE DISTRIBUTION;

EID: 0034937833     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (3)

1. Metabolism of tetramethrin isomers in rat. I. Identification of a sulphonic acid type of conjugate and reduced metabolites
2. Biotransformation of the antipsychotic agent, mazapertine, in dog-mass spectral characterization and identification of metabolites