Molecular interactions of vasoactive systems in cardiovascular damage

Journal of Cardiovascular Pharmacology

Volumn 38, Issue SUPPL. 2, 2002, Pages

  Bader, M ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

ACE inhibitors; Fibrosis; Hypertrophy; Kallikrein kinin system; Renin angiotensin system; Transgenic animals

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 2 RECEPTOR; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; KALLIKREIN; KININ; PRORENIN;

CONFERENCE PAPER; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; HEART DISEASE; HYPERTENSION; KALLIKREIN KININ SYSTEM; KIDNEY INJURY; MOLECULAR INTERACTION; PATHOGENESIS; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

EID: 0036135752     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200111002-00003     Document Type: Conference Paper

References (13)

1. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients
2. Potentiation of the vascular response to kinins by inhibition of myocardial kininases
3. Potentiation of bradykinin action by ACE inhibitors
4. AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration
5. Prorenin processing and restricted endoproteolysis by mouse tissue kallikrein family enzymes (mK1, mK9, mK13, and mK22)
6. Reduced cardiac hypertrophy and altered blood pressure control in transgenic rats with the human tissue kallikrein gene
7. Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation
8. Reduction of cardiac hypertrophy in TGR(mREN2)27 by angiotensin II receptor blockade
9. Hypertension-induced end-organ damage: A new transgenic approach to an old problem
10. Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling
11. Overexpression of the human angiotensin II type 1 receptor in the rat heart augments load induced cardiac hypertrophy
12. Human kallikrein gene delivery attenuates hypertension, cardiac hypertrophy, and renal injury in Dahl salt-sensitive rats
13. Increased kallikrein expression protects against cardiac ischemia