Tissue transglutaminase and coeliac disease pathogenesis: Potential molecular mechanisms for other human diseases

Neurochemistry International

Volumn 40, Issue 1, 2002, Pages 79-83

  Gentile, Vittorio ^a   Violante, Vittorio ^a   D'Amico, Bonifacio ^a   Illiano, Michele ^a   Luongo, Antonio ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

Coeliac disease; Human disease; Tissue transglutaminase

Indexed keywords

GLIADIN; INTESTINE ENZYME; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

CELIAC DISEASE; CONFERENCE PAPER; DISEASE ASSOCIATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; HUMAN; MOLECULAR BIOLOGY; PATHOGENESIS; PRIORITY JOURNAL; PSYCHOPATHY; SCHIZOPHRENIA; SPINOCEREBELLAR DEGENERATION;

CELIAC DISEASE; HUMANS; MENTAL DISORDERS; NERVOUS SYSTEM DISEASES; TRANSGLUTAMINASES;

EID: 0036134823     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(01)00063-8     Document Type: Conference Paper

References (23)

1. In vivo antigen challenge in celiac disease identifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope
2. The intestinal T cell response to α-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase
3. Amines protect in vitro the celiac small intestine from the damaging activity of gliadin peptides
4. Human jejunal transglutaminase: Demonstration of activity, enzyme kinetics and substrate specificity with special relation to gliadin and coeliac disease
5. n-expansion diseases with special reference to the role of tissue transglutaminase and to selective vulnerability
6. Clinical and biological characteristics of gluten intolerance
7. Huntington's disease, transglutaminase and celiac disease
8. The length of polyglutamine tract, its level of expression, the rate of degradation, and the transglutaminase activity influence the formation of intracellular aggregates
9. Identification of tissue transglutaminase as the autoantigen of coeliac disease
10. Mechanism and basis for specificity of transglutaminase-catalyzed ε-(γ-glutamyl)lysine bond formation
11. Tissue transglutaminase-catalyzed formation of high-molecular-weight aggregates in vitro is favored with long polyglutamine domains: A possible mechanism contributing to CAG-triplet diseases
12. Coeliac disease, epilepsy, and cerebral calcifications
13. Human genetic diseases due to codon reiteration: Relationship to an evolutionary mechanism
14. Neurological and psychiatric complications in coeliac disease
15. Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch
16. Transglutaminases
17. Coeliac disease and schizophrenia
18. Role of tissue transglutaminase in coeliac disease
19. Cereal dietary proteins with sites for cross-linking by transglutaminase
20. The ρ-deamidating cytotoxic necrotizing factor 1 from Escherichia coli possesses transglutaminase activity: Cysteine 866 and histidine 881 are essential for enzyme activity
21. HLA susceptibility genes in celiac disease: Genetic mapping and role in pathogenesis
22. Differential distribution of tissue transglutaminase in human cells: An immunohistochemical study
23. Celiac sprue