Mutation of bcl-x gene in non-Hodgkin's lymphoma

American Journal of Hematology

Volumn 69, Issue 1, 2002, Pages 74-76

  O'Shea, Susan I ^a   Sands, Jeffrey J ^a   Nudo, Sybil A ^a   Ortel, Thomas L ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Bcl xl; Bcl xs; Mutation; Non Hodgkin's lymphoma

Indexed keywords

GLYCINE; PROTEIN BCL X; SERINE;

ARTICLE; B CELL LYMPHOMA; BONE MARROW BIOPSY; CARCINOGENESIS; CLINICAL ARTICLE; CODON; CONTROLLED STUDY; GENE SEQUENCE; HUMAN; HUMAN CELL; MISSENSE MUTATION; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCREENING; SEQUENCE ANALYSIS; SINGLE STRAND CONFORMATION POLYMORPHISM;

APOPTOSIS; BCL-X PROTEIN; GLYCINE; HUMANS; LYMPHOMA, NON-HODGKIN; MUTATION; MUTATION, MISSENSE; POINT MUTATION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SERINE;

EID: 0036134079     PISSN: 03618609     EISSN: None     Source Type: Journal    
DOI: 10.1002/ajh.10030     Document Type: Article

References (9)

1. Molecular thanatopsis: A discourse on the bcl-2 family and cell death
2. A revised European-American classification of lymphoid neoplasms: A proposal from the International Lymphoma Study Group
3. Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction
4. Heterogenous expression of bcr-abl fusion mRNA in a patient with Philadelphia-chromosome-positive acute lymphoblastic leukaemia
5. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
6. Cloning and molecular characterization of mouse bcl-x in B and T lymphocytes
7. Morphologic transformation of follicular lymphoma is associated with somatic mutation of the translocated bcl-2 gene
8. Bax mutations in cell lines derived from hematological malignancies
9. Hematopoietic malignancies demonstrate loss of function mutation of BAX