Prognostic significance of thymidine phosphorylase and p53 co-expression in esophageal squamous cell carcinoma

Oncology Reports

Volumn 9, Issue 1, 2002, Pages 23-28

  Makoto, Oota ^a   Takeda, Akihiko ^a   Ting Leig, Leu ^a   Shinnichi, Okazumi ^a   Hisahiro, Matsubara ^a   Yutaka, Funami ^a   Yoshihiro, Nabeya ^a   Kobayashi, Susumu ^a   Gunji, Yoshio ^a   Suzuki, Takao ^a   Takenori, Ochiai ^a   Hideaki, Shimada ^a  

^a CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Esophageal cancer; p53; Prognostic factor; Squamous cell carcinoma; Thymidine phosphorylase

Indexed keywords

PROTEIN P53; THYMIDINE PHOSPHORYLASE;

AGED; ARTICLE; ENZYME IMMUNOASSAY; ENZYMOLOGY; ESOPHAGUS TUMOR; FEMALE; HUMAN; MALE; METABOLISM; PROGNOSIS; SQUAMOUS CELL CARCINOMA; SURVIVAL;

AGED; CARCINOMA, SQUAMOUS CELL; ESOPHAGEAL NEOPLASMS; FEMALE; HUMAN; IMMUNOENZYME TECHNIQUES; MALE; PROGNOSIS; PROTEIN P53; SUPPORT, NON-U.S. GOV'T; SURVIVAL ANALYSIS; THYMIDINE PHOSPHORYLASE;

EID: 0036133899     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.9.1.23     Document Type: Article

References (32)

1. Daly JM, Karnell LH and Mehck HR: National cancer data base report on esophageal carcinoma. Cancer 78: 1820-1828, 1996. (Pubitemid 26330913)
2. Kato H, Tachimori Y, Watanabe H and Iizuka T: Evaluation of the new (1987) TNM classification for thoracic esophageal tumors. Int J Cancer 53: 220-223, 1993. (Pubitemid 23042869)
3. Folkman J: What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 82: 4-6, 1990.
4. Haraguchi M, Miyadeara A, Uemura K, Sumizawa T, Furukawa T, Yamada K, Akiyama S and Yamada Y: Angiogenic activity of enzymes. Nature 368: 198, 1994.
5. Griffiths L and Stratford IJ: Platelet-derived endothelial cell growth factor thymidine phosphorylase in tumor growth and response to therapy. Br J Cancer 76: 689-693, 1997. (Pubitemid 27379732)
6. Kitadai Y, Haruma K, Tokutomi T, Tanaka S, Sumii K, Carvalho M, Kuwabara M, Yoshida K, Hirai T, Kajiyama G and Tahara E: Significance of vessel count and vascular endothelial growth factor in human esophageal carcinomas. Clin Cancer Res 4: 2195-2200, 1998. (Pubitemid 28415667)
7. Shih CH, Ozawa S, Ando N, Ueda M and Kitajima M: Vascular endothelial growth factor expression predicts outcome and lymph node metastasis in squamous cell carcinoma of the esophagus. Clin Cancer Res 6: 1161-1168, 2000. (Pubitemid 30159380)
8. Inoue K, Ozeki Y, Suganuma T, Sugiura Y and Tanaka S: Vascular endothelial factor expression in primary esophageal squamous cell carcinoma. Cancer 79: 206-213, 1997.
9. Takahashi Y, Bucana CD, Liu W, Yoneda J, Kitadani Y, Cleary KR and Ellis LM: Platelet-derived endothelial cell growth factor in human colon cancer angiogenesis: role of infiltrating cells. J Natl Cancer Inst 88: 1146-1151, 1996. (Pubitemid 26274608)
10. Maeda K, Kang SM, Ogawa M, Onnoda N, Sawada T, Nakata B, Kato Y, Chung YS and Sowa M: Combined analysis of vascular endothelial cell growth factor and platelet-derived endothelial cell growth factor expression in gastric cancer. Int J Cancer 74: 545-550, 1997. (Pubitemid 27486514)
11. Fujiwaki R, Hata K, Iida K, Maede Y and Miyazaki K: Vascular endothelial cell growth factor expression in progression of cervical cancer: correlation with thymidine phosphorylase expression, angiogenesis, tumor cell proliferation, and apoptosis. Anticancer Res 20: 1317-1322, 2000. (Pubitemid 30240721)
12. Igarashi M, Dhar DK, Kubota H, Yamamoto A, EL-Assal O and Nagasue N: The profnostic significance of micro vessel density and thymidine phosphorylase expression in squamous cell carcinoma of the esophagus. Cancer 82: 1225-1232, 1997. (Pubitemid 28155382)
13. Takebayashi Y, Natsugoe S, Baba M, Akiba S, Fukumoto T, Miyadera K, Yamada Y, Takao S, Akiyama S and Aikou T: Thymidine phosphorylase in human esophageal squamous cell carcinoma. Cancer 85: 282-289, 1999. (Pubitemid 29051280)
14. Mori K, Hasegawa M, Nishida M, Toma H, Fukuda M, Kubota T, Nagasue N, Yamana H, Chung K, Ikeda T, Takasaki K, Oka M, Kameyama M, Toi M, Fujii H, Kitamura M, Murai M, Sasaki H, Ozono S, Makuuchi H, Shimada Y, Onishi Y, Aoyagi S, Mizutani K, Ogawa M, Nakao A, Kinoshita H, Tono T, Imamoto H, Nakashima Y and Manabe T: Expression levels of thymidine phosphorylase and dihydropyrimidine dehydrogenase in various human tumor tissues. Int J Oncol 17: 33-38, 2000.
15. Ikeguchi M, Oka S, Saito H, Kondo A, Tsujitani S, Maeta M and Kaibara N: Clinical significance of the detection of thymidine phosphorylase activity in esophageal squamous cell carcinoma. Eur Surg Res 31: 357-363, 1999. (Pubitemid 29381172)
16. Saito S, Tsuno N, Nagawa H, Sunami E, Zhengxi J, Osada T, Kitayama J, Shinbata Y, Tsuruo T and Muto T: Expression of pletelet-derived endothelial cell growth factor correlates with good prognosis in patients with colorectal carcinoma. Cancer 88: 42-49, 2000. (Pubitemid 30027677)
17. Soussi T, Legros Y, Lubin R, Ory K and Schlichtholz B: Multi factorial analysis of p53 alteration in human cancer: a review. Int J Cancer 57: 1-9, 1994. (Pubitemid 24117091)
18. Kobayashi S, Koide Y, Endo M, Isono K and Ochiai T: The p53 gene mutation is of prognostic value in esophageal squamous cell carcinoma patients in unified stage of curability. Am J Surg 177: 497-502, 1999. (Pubitemid 29331482)
19. Sarbia M, Porschen R, Borchard F, Horstmann O and Willers R: p53 protein expression and prognosis in squamous cell carcinoma of the esophagus. Cancer 74: 2218-2223, 1994.
20. Ribeiro U Jr, Finkelstein SD, Safatle-Ribeiro AV, Landreneau RJ, Clarke MR, Bakker A, Swalsky PA, Gooding WE and Posner MC: p53 sequence analysis predicts treatment response and outcome of patients with esophageal carcinoma. Cancer 83: 7-18, 1998. (Pubitemid 28299623)
21. Uchida S, Shimada Y, Watanabe G, Tanaka H, Shibazaki I, Miyahara T, Ishigami S, Arii S and Imamura M: In esophageal squamous cell carcinoma vascular endothelial growth factor is associated with p53 mutation, advanced stage and poor prognosis. Br J Cancer 77: 1704-1709, 1998. (Pubitemid 28230478)
22. Casson AG, Tammemagi M, Eskandarian S, Redston M, McLaughlin J and Ozcelik H: p53 alterations in esophageal cancer: association with clinicopathological features, risk factors, and survival. Mol Pathol 51: 71-79, 1998. (Pubitemid 28261244)
23. Takahashi Y, Bucana CD, Clearly KR and Ellis LM: p53, vessel count and vascular endothelial growth factor expression in human colon cancer. Int J Cancer 79: 34-38, 1998. (Pubitemid 28157723)
24. Linderholm BK, Lindahl T, Holmberg L, Klaar S, Lennerstrand J, Henriksson R and Bergh J: The expression of vascular endothelial cell growth factor correlates with mutant p53 and poor prognosis in human breast cancer. Cancer Res 61: 2256-2260, 2001. (Pubitemid 32692056)
25. Giatromanolaki A, Fountzilas G, Koukourakis MI, Arapandoni P, Theologi V, Kakolyris S, Georgoulias V, Harris AL and Gatter KC: Neo-angiogenesis in locally advanced squamous cell head and neck cancer correlates with thymidine phosphorylase expression and p53 nuclear oncoprotein accumulation. Clin Exp Metastasis 16: 665-672, 1998. (Pubitemid 29044589)
26. UICC TNM Classification of Malignant Tumor. Sobin LH and Wittekind CH (eds). 5th edition. John Wiley and Sons Inc., 1997.
27. Hsu SM, Raine L and Fanger AH: A comparative study of the peroxidase method and an avidine-biotin complex method for studying polypeptide hormones with radioimmunoassay antibody. Am J Clin Pathol 75: 734-738, 1981. (Pubitemid 11117256)
28. Fujieda S, Sunaga H, Tsuzuki H, Tanaka N and Saito H: Expression of platelet-derived endothelial cell growth factor in oral and oropharyngeal carcinoma. Clin Cancer Res 4: 1583-1590, 1998. (Pubitemid 28304717)
29. O'Brien TS, Fox SB, Dickinson AJ, Turley H, Westwood M, Moghaddam A, et al: Expression of the angiogenic factor thymidine phosphorylase/platelet-derived endothelial cell growth factor in primary bladder cancers. Cancer Res 56: 4799-4804, 1996. (Pubitemid 26338087)
30. Mukhopadhyay D, Tsiokas L and Sukhatme VP: Wild-type p53 and v-Src exert opposing influences on human vascular endothelial growth factor gene expression. Cancer Res 55: 6161-6165, 1995.
31. Bouvet M, Ellis LM, Nishizaki M, Fujiwara T, Liu W, Bucana CD, Fang B, Lee JJ and Roth JA: Adenovirus-mediated wild-type p53 gene transfer down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human colon cancer. Cancer Res 58: 2288-2292, 1998. (Pubitemid 28252680)
32. Matsushita S, Nitanda T, Furukawa T, Sumizawa T, Tani A, Nishimoto K, Akiba S, Miyadera K, Fukushima M, Yamada Y, Yishida H, Kanzaki T and Akiyama S: The effect of a thymidine phosphorylase inhibitor on angiogenesis and apoptosis in tumors. Cancer Res 59: 1911-1916, 1999. (Pubitemid 29186165)