Bone cement extracts modulate the osteoprotegerin/osteoprotegerin-ligand expression in MG63 osteoblast-like cells

Biomaterials

Volumn 23, Issue 11, 2002, Pages 2359-2365

  Granchi, Donatella ^a   Cenni, Elisabetta ^a   Savarino, Lucia ^a   Ciapetti, Gabriela ^a   Forbicini, Giulia ^a   Vancini, Melania ^a   Maini, Cecilia ^a   Baldini, Nicola ^a   Giunti, Armando ^a  

^a RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

Author keywords

Bone cements; Hip prosthesis; Osteolysis; Osteoprotegerin; Osteoprotegerin ligand

Indexed keywords

BONE CEMENT; CELLS; POLYMERIZATION; POLYMETHYL METHACRYLATES;

OSTEOCLASTS;

BIOMATERIALS;

BONE CEMENT; CMW 1; CMW 2; CMW 3; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; POLY(METHYL METHACRYLATE); RECOMBINANT INTERLEUKIN 1BETA; SULFIX 60; UNCLASSIFIED DRUG;

ARTICLE; BONE REMODELING; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; CULTURE MEDIUM; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TECHNIQUE;

BONE CEMENTS; CARRIER PROTEINS; CELL LINE; GENE EXPRESSION; GLYCOPROTEINS; HUMANS; MATERIALS TESTING; MEMBRANE GLYCOPROTEINS; OSTEOBLASTS; OSTEOLYSIS; OSTEOPROTEGERIN; POLYMETHYL METHACRYLATE; PROSTHESIS FAILURE; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, TUMOR NECROSIS FACTOR; RNA, MESSENGER;

EID: 0036130224     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(01)00371-4     Document Type: Article

References (37)

1. Anchorage of the femoral head prosthesis to the shaft of the femur
2. Innovations in acrylic bone cement and application equipment
3. The femoral stem/cement interface in total hip replacement
4. The problem is osteolysis
5. Microstructural investigation of bone-cement interface
6. Cell cycle of osteoblast-like cells after in vitro exposure to bone cements
7. In vitro cytokine production by mononuclear cells exposed to bone cement extracts
8. Bone-resorbing cytokines in serum of patients with aseptic loosening of hip prostheses
9. Cytokines and osteolysis around total hip prostheses
10. PMMA induce inflammatory macrophages resorb bone
11. Human arthroplasty macrophages differentiate into osteoclastic bone resorbing cells
12. Osteoprotegerin (OPG) ligand is a cytokine that regulates osteoclast differentiation and activation
13. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
14. The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption
15. Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand
16. Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG); a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro
17. Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis
18. Osteoclastogenesis-inhibitory factor suppresses osteoclast survival by interfering in the interaction of stromal cells with osteoclast
19. Characterization of a novel TNF-like ligand and recently described TNF ligand and TNF receptor superfamily genes and their constitutive and inducible expression in hematopoietic and non-hematopoietic cells
20. Molecular control of bone remodeling and osteoporosis
21. Effects of osteoprotegerin and osteoprotegerin ligand on osteoclast formation by arthroplasty membrane derived macrophages
22. Interleukin-1β and tumor necrosis factor-α, but not interleukin-6 stimulate osteoprotegerin ligand gene expression in human osteoblastic cells
23. In vitro testing of ten bone cements after different time intervals from polymerization
24. New insights into an old protein; the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase
25. Modulation of pro- and anti-apoptotic genes in lymphocytes exposed to bone cements
26. Cytotoxic effect of bone cements in HL-60 cells; distinction between apoptosis and necrosis
27. Modification of macrophage glyceraldehyde-3-phosphate dehydrogenase in response to nitric oxide
28. Cell cycle regulation of the glyceraldehyde-3-phosphate dehydrogenase/uracil DNA glycosylase gene in normal human cells
29. In vitro release studies of methylmethacrylate liberation from acrylic cement powder
30. Production of cytokines around loosened cemented acetabular components. Analysis with immunohistochemical techniques and in situ hybridization
31. Tumor necrosis factor-alpha mediates orthopedic implant osteolysis
32. Coordinated cytokine expression by stromal and hematopoietic cells during human osteoclast formation
33. TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand
34. The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated
35. Increased osteoclastic differentiation by PMMA particle-associated macrophages. Inhibitory effect by interleukin 4 and leukemia inhibitory factor
36. Radio-opaque agents in bone cement increase bone resorption