Effects of gatifloxacin on phagocytosis, intracellular killing and oxidant radical production by human polymorphonuclear neutrophils

International Journal of Antimicrobial Agents

Volumn 19, Issue 3, 2002, Pages 183-187

  Braga, P C ^a,c   Dal Sasso, M ^a   Bovio, C ^a   Zavaroni, E ^b   Fonti, E ^b  

^a Institute of Psychology   (Italy)

^b OSPEDALE NIGUARDA CA GRANDA   (Italy)

^c Address: Centro di Farmacologia Respiratoria   (Italy)

Author keywords

Escherichia coli; Gatifloxacin; Killing; Oxidative burst; Phagocytosis; Polymorphonuclear neutrophil

Indexed keywords

GATIFLOXACIN;

ARTICLE; DOSE RESPONSE; ENTEROBACTER INFECTION; HOST RESISTANCE; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; PHAGOCYTOSIS; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; RESPIRATORY BURST;

ANTI-INFECTIVE AGENTS; CELLS, CULTURED; ESCHERICHIA COLI; FLUOROQUINOLONES; HUMANS; MICROBIAL SENSITIVITY TESTS; NEUTROPHILS; OXIDATION-REDUCTION; PHAGOCYTOSIS; RESPIRATORY BURST;

EID: 0036128763     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-8579(02)00007-9     Document Type: Article

References (22)

1. The antibacterial effects of low concentrations of antibiotics
2. Bactericidal activity of phenoxymethyl-penicillin in an in-vitro model stimulating tissue kinetics
3. Pharmacodynamic effects of subinhibitory concentrations of β-lactam antibiotics in vitro
4. Effect of subinhibitory antibiotic concentrations on the phagocytosis of Staphylococcus aureus
5. Enhanced phagocytosis of encapsulated Escherichia coli strains after exposure to sub-MICs of antibiotics is correlated to changes of the bacterial cell surface
6. Some effects of subinhibitory concentrations of antibiotics on bacteria
7. Phagocytosis and intracellular killing of rokitamycin-exposed staphylococci by human polymorphonuclear leukocytes
8. Evaluation of a fluorochrome assay for assessing the bactericidal activity of neutrophils in human phagocyte dysfunctions
9. The extinction of fluorescence by crystal violet and its use to differentiate between attached and ingested microorganisms in phagocytosis
10. Bacterial phagocytosis monitored by fluorescence and extracellular quenching: ingestion and intracellular killing
11. Chemiluminescence response to pathogenic organisms: normal human polymorphonuclear leukocytes
12. Single- and multiple-dose pharmacokinetics of AM-1155, a new 6-fluoro-8-methoxy quinolone, in humans
13. Influence of various antimicrobial agents on the chemiluminescence of phagocytosing human granulocytes
14. Enhanced chemiluminescence response of polymorphonuclear leukocytes by new quinolone antimicrobials
15. Effects of the quinolones on the immune system
16. Pharmacodynamic effects of subinhibitory concentrations of rufloxacin on bacterial virulence factors
17. Effect of ciprofloxacin on phagocytosis
18. Investigations on ofloxacin: antibacterial activity and influence on the immune system
19. Effect of low concentrations of quinolone antibiotics on bacterial virulence mechanisms
20. Lomefloxacin induced modification of the kinetics of growth of Gram-negative bacteria and susceptibility to phagocytic killing by human neutrophils
21. Intraphagocytic killing of Gram-positive bacteria by ciprofloxacin
22. Uptake and intracellular activity of AM-1155 in phagocytic cells