Dynamical characterization of residual and non-native structures in a partially folded protein by 15N NMR relaxation using a model based on a distribution of correlation times

Protein Science

Volumn 11, Issue 4, 2002, Pages 957-964

  Ochsenbein, Françoise ^a,b,c   Neumann, Jean Michel ^a,b,c   Guittet, Eric ^a,b,c   Van Heijenoort, Carine ^a,b,c  

^a INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES   (France)

^b Section de Biophysique des Protéines et des Membranes   (France)

^c CNRS   (France)

Author keywords

15N relaxation; Distribution of correlation times; Dynamics; Models; Proteins; Unfolded states

Indexed keywords

LIPOCORTIN 1;

ARTICLE; CHEMICAL BOND; CORRELATION ANALYSIS; MAGNETIC FIELD; MATHEMATICAL MODEL; MEASUREMENT; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; SPECTROMETRY;

ANNEXIN A1; MAGNETICS; MODELS, MOLECULAR; NITROGEN ISOTOPES; NONLINEAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN FOLDING;

LORENTZIA;

EID: 0036127432     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.4000102     Document Type: Article

References (37)

1. Backbone dynamics of a highly disordered 131 residue fragment of staphylococcal nuclease
2. Backbone dynamics and structural characterization of the partially folded A state of ubiquitin by 1H, 13C, and 15N nuclear magnetic resonance spectroscopy
3. Main-chain dynamics of a partially folded protein: 15N NMR relaxation measurements of hen egg white lysozyme denatured in trifluoroethanol
4. Dynamics of unfolded proteins: Incorporation of distributions of correlation times in the model free analysis of NMR relaxation data
5. Backbone dynamics of the natively unfolded pro-peptide of subtitisin by heteronuclear NMR relaxation studies
6. Deviation from the simple two-parameters model-free approach to the interpretation of nitrogen-15 nuclear magnetic relaxation of proteins
7. Folding properties of an annexin I domain: A IH-15N NMR and CD study
8. Exploring the folding pathways of annexin I, a multidomain protein. I. Non-native structures stabilize the partially folded state of the isolated domain 2 of annexin I
9. Carbon-13 NMR investigation of local dynamics in bulk polymers at temperatures well above the glass transition temperature. I. Poly(vinyl methyl ether)
10. Study of dynamic processes in liquids using off-resonance rf irradiation processes
11. Equilibrium NMR studies of unfolded and partially folded proteins
12. Nuclear magnetic resonance methods for elucidation of structures and dynamics in disordered states
13. Native and nonnative secondary structure and dynamics in the pH 4 intermediate of apomyoglobin
14. Structural and dynamic characterization of partially folded states of apomyoglobin and implications for protein folding
15. Characterization of the backbone dynamics of folded and denatured states of an SH3 domain
16. Structural and dynamic characterization of the urea denatured state of the immunoglobulin binding domain of streptococcal protein G by multidimensional heteronuclear NMR spectroscopy
17. Nuclear magnetic relaxation of synthetic polymers in dilute solutions
18. Nuclear magnetic relaxation and models for backbone motions of macromolecules in solution
19. Crystal and molecular structure of human annexin V after refinement. Implications for structure, membrane binding and ion channel formation of the annexin family of proteins
20. Structural characterization of the molten globule of alpha-lactalbumin by solution X-ray scattering
21. Structural characterization of the molten globule and native states of apomyoglobin by solution X-ray scattering
22. The effect of helixcoil transition on backbone 15N NMR relaxation of isolated transmembrane segment (1-36)-bacteriorhodopsin
23. Mechanism of the unfolding of transmembrane a-helical segment (1-36)-bacteriorhodopsin studied by dynamics simulations
24. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
25. Longitudinal and transverse 1H-15N dipolar/15N chemical shift anisotropy relaxation interference: Unambiguous determination of rotational diffusion tensors and chemical exchange effects in biological macromolecules
26. Model-free approach to the interpretation of nuclear magnetic resonance relaxation in macromolecule. 1. Theory and range of validity
27. Backbone dynamics of Escherichia coli ribonuclease HI: Correlations with structure and function in an active enzyme
28. Probing residual structure and backbone dynamics on the milli- to picosecond timescale in a urea-denatured fibronectin type III domain
29. An off-resonance rotating frame relaxation experiment for the investigation of macromolecular dynamics using adiabatic rotations
30. 15N NMR relaxation as a probe for helical intrinsic propensity: The case of the unfolded D2 domain of annexin I
31. Sampling of protein dynamics in nanosecond time scale by 15N NMR relaxation and self-diffusion measurements
32. Intramolecular motions of a zinc finger DNA-binding domain from Xfin characterized by proton-detected natural abundance 13C heteronuclear NMR spectroscopy
33. Dynamic studies of a fibronectin type I module pair at three frequencies: Anisotropic modelling and direct determination of conformational exchange
34. Structural and dynamical properties of a denatured protein. Heteronuclear 3D NMR experiments and theoretical simulations of lysozyme in 8 M urea
35. Dynamics of the DNA binding domain of the fructose repressor from the analysis of linear correlations between the 15N-1H bond spectral densities obtained by nuclear magnetic resonance spectroscopy
36. Crystal structure of human annexin I at 2.5 Å resolution