Investigation of the effect of chlormethiazole on cerebral chemistry in neurosurgical patients: A combined study of microdialysis and a neuroprotective agent

British Journal of Clinical Pharmacology

Volumn 53, Issue 3, 2002, Pages 275-283

  Hutchinson, P J ^a   O'Connell, M T ^a   Coles, J P ^a   Chatfield, D A ^a   Coleman, M R ^a   Al Rawi, P G ^a   Kett White, C R ^a   Gupta, A K ^a   Menon, D K ^a   Boniface, S J ^a   Heazell, M ^a   Kirkpatrick, P J ^a   Pickard, J D ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Cerebral metabolism; Chlormethiazole; Head injury; Microdialysis; Neuroprotection

Indexed keywords

4 AMINOBUTYRIC ACID; AMINO ACID; ATRACURIUM; CLOMETHIAZOLE; FENTANYL; GLUCOSE; GLUTAMIC ACID; LACTIC ACID; NEUROPROTECTIVE AGENT; PROPOFOL; PYRUVIC ACID;

ADULT; ARTERIAL CARBON DIOXIDE TENSION; ARTERIAL OXYGEN TENSION; ARTERIAL PH; ARTICLE; ASSAY; BRAIN PERFUSION; BRAIN TEMPERATURE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG EFFECT; DRUG INFUSION; DRUG SAFETY; DRUG TOLERANCE; ELECTROENCEPHALOGRAPHY; FEMALE; GLUCOSE BLOOD LEVEL; HEAD INJURY; HEART RATE; HUMAN; INTENSIVE CARE UNIT; INTRACRANIAL PRESSURE; MALE; MEAN ARTERIAL PRESSURE; MICRODIALYSIS; NEUROPHYSIOLOGY; NEUROPROTECTION; NEUROSURGERY; OXYGEN SATURATION; OXYGEN TISSUE LEVEL; PRIORITY JOURNAL;

ADULT; BRAIN CHEMISTRY; CHLORMETHIAZOLE; COMBINED MODALITY THERAPY; CRANIOCEREBRAL TRAUMA; ELECTROENCEPHALOGRAPHY; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; INTENSIVE CARE UNITS; INTRACRANIAL PRESSURE; MALE; MICRODIALYSIS; MIDDLE AGED; MONITORING, PHYSIOLOGIC; NEUROPROTECTIVE AGENTS;

EID: 0036121962     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0306-5251.2001.01552.x     Document Type: Article

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