An open study of clomethiazole in patients with acute cerebral infarction [1]

Cerebrovascular Diseases

Volumn 8, Issue 3, 1998, Pages 188-190

  Wester, Per ^a   Strand, Tage ^a   Wahlgren, Nils Gunnar ^b   Ashwood, Tim ^c   Osswald, Gunilla ^c  

^a UMEÅ UNIVERSITY   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c Astra Arcus AB   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CLOMETHIAZOLE;

BRAIN INFARCTION; BRONCHOSPASM; CLINICAL TRIAL; COUGHING; DYSPNEA; EUPHORIA; FATIGUE; FEVER; HEADACHE; HICCUP; HUMAN; INJECTION SITE; INTRAVENOUS DRUG ADMINISTRATION; LETTER; NAUSEA; PAIN; PHARYNX DISEASE; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; PULSE RATE; RHINITIS; SALIVATION DISORDER; SIDE EFFECT; SPUTUM; STROKE; SYNCOPE; TACHYCARDIA; URINARY TRACT INFECTION; YAWNING;

EID: 0031923216     PISSN: 10159770     EISSN: None     Source Type: Journal    
DOI: 10.1159/000015846     Document Type: Letter

References (7)

1. Shuaib A, Ijaz S, Kanthan R: Clomethiazole protects the brain in transient forebrain ischemia when used up to 4 h after insult. Neurosci Lett 1995; 197:109-112.
2. Cross A, Jones J, Snares M, Jostell K, Bredberg U, Green A: The protective action of chlormethiazole against ischaemia-induced neurodegeneration in gerbils when infused at doses having little sedative or anticonvulsant activity. Br J Pharmacol 1995;114:1625-1630.
3. Sydserff S, Cross A, West K, Green A: The effect of chlormethiazole on neuronal damage in a model of transient focal ischemia. Br J Pharmacol 1995;114:1631-1635.
4. Sydserff S, Cross A, Green A: The neuroprotective effect of chlormethiazole on ischaemic neuronal damage following permanent middle cerebral artery ischaemia in the rat. Neurodegeneration 1995;4:323-328.
5. Snape M, Baldwin H, Cross A, Green A: The effects of chlormethiazole and nimodipine on cortical infarct area after focal cerebral ischaemia in the rat. Neuroscience 1993;53:837-844.
6. Green A, Cross A: Attenuation by chlormethiazole of oedema following focal ischaemia in the cerebral cortex of the rat. Neurosci Lett 1994;173: 27:30.
7. Hewitt K, Green A: Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA ('Ecstasy') to rats. Neuropharmacology 1994;33:1589-1595.