Subthalamic 5-HT1A and 5-HT1B receptor modulation of RU 24969-induced behavioral profile in rats

Pharmacology Biochemistry and Behavior

Volumn 71, Issue 4, 2002, Pages 569-580

  Martinez Price, Diana L ^a   Geyer, Mark A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

5 HT1A; 5 HT1B; 8 OH DPAT; CP 93,129; Locomotion; RU 24969; Subthalamic nucleus

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 3 (1,2,5,6 TETRAHYDRO 4 PYRIDYL)PYRROLO[3,2 B]PYRIDIN 5 ONE; 5 METHOXY 3 (1,2,3,6 TETRAHYDRO 4 PYRIDYL) 1H INDOLE; SEROTONIN 1A AGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN 1B AGONIST; SEROTONIN 1B RECEPTOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; LOCOMOTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; RECEPTOR UPREGULATION; SUBSTANTIA NIGRA; SUBTHALAMIC NUCLEUS;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; BEHAVIOR, ANIMAL; DRUG INTERACTIONS; EXPLORATORY BEHAVIOR; INDOLES; MALE; MICROINJECTIONS; MOTOR ACTIVITY; PYRIDINES; PYRROLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, SEROTONIN, 5-HT1B; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN AGONISTS; SUBSTANTIA NIGRA; SUBTHALAMUS;

EID: 0036121164     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(01)00704-3     Document Type: Article

References (48)

1. The pathophysiology of chorea/ballism and parkinsonism
2. The functional anatomy of basal ganglia disorders
3. Reversal of experimental parkinsonism by lesions of the subthalamic nucleus
4. Evidence that 5-HT agonist-induced rotational behaviour in the rat is mediated via 5-HT1 receptors
5. Autoradiographic characterisation and localisation of 5-HT1D compared to 5-HT1B binding sites in rat brain
6. Tolerance and cross-tolerance to the activating effects of 3,4-methylenedioxymethamphetamine and a 5-hydroxytryptamine1B agonist
7. Serotonin release contributes to the locomotor stimulant effects of 3,4-methylenedioxymethamphetamine in rats
8. Serotonin 5-HT1-like receptors mediate hyperactivity in rats induced by 3,4-methylenedioxymethamphetamine
9. The 5HT (1B) receptor agonist, CP-93129, inhibits [(3)H]-GABA release from rat globus pallidus slices and reverses akinesia following intrapallidal injection in the reserpine-treated rat
10. Evidence that RU 24969-induced locomotor activity in C57/B1/6 mice is specifically mediated by the 5-HT1B receptor
11. Injections of D-amphetamine into the ventral pallidum increase locomotor activity and responding for conditioned reward: A comparison with injections into the nucleus accumbens
12. 5-Hydroxytryptamine increases spontaneous activity of subthalamic neurons in the rat
13. Multivariate and nonlinear approaches to characterizing drug effects on the locomotor and investigatory behavior of rats
14. Multivariate assessment of locomotor behavior: Pharmacological and behavioral analyses
15. Dissociation of locomotor and conditioned place preference responses following manipulation of GABA-A and AMPA receptors in ventral pallidum
16. 1D receptors in the substantia nigra of the guinea-pig elicits contralateral rotation
17. Afferents to the rat substantia nigra studied with horseradish peroxidase, with special reference to fibres from the subthalamic nucleus
18. Toward an understanding of the role of glutamate in experimental parkinsonism: Agonist-sensitive sites in the basal ganglia
19. 1A receptors in the locomotor-suppressant effects of LSD: WAY-100635 studies of 8-OH-DPAT, DOI, and LSD
20. Concomitant characterization of behavioral and striatal neurotransmitter response to amphetamine using in vivo microdialysis
21. 3-(1,2,5,6-tetrahydropyrid-4yl)pyrrolo[3,2-b]pyrid-5-one: A potent and selective serotonin (5-HT1B) agonist and rotationally restricted phenolic analogue of 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4yl)indole
22. A 5-HT1B antagonist blocks effects of RU 24969 on locomotor, but not investigatory, activity in rats
23. Site-specific effects and dissociation of RU 24969-induced changes in locomotor activity and investigatory holepokes
24. Stimulation of the rat subthalamic nucleus enhances the release of dopamine in the rat substantia nigra
25. Effects of 5HT-1A agonists on locomotor and investigatory behaviors in rats differ from those of hallucinogens
26. Electrical membrane properties of rat subthalamic neurons in an in vitro slice preparation
27. Intracellular study of rat substantia nigra pars reticulata neurons in an in vitro slice preparation: Electrical membrane properties and response characteristics to subthalamic stimulation
28. Distinct functions for dopamine and serotonin in locomotor behaviour: Evidence using the 5-HT1 agonist RU 24969 in globus pallidus-lesioned rats
29. RU24969-induced behavioural syndrome requires activation of both 5HT1A and 5HT1B receptors
30. GR46611 potentiates 5-HT1A receptor-mediated locomotor activity in the guinea pig
31. A scaling approach to find order parameters quantifying the effects of dopaminergic agents on unconditioned motor activity in rats
32. A temporal and spatial scaling hypothesis for the behavioral effects of psychostimulants
33. The effects of MDMA and other methylenedioxy-substituted phenylalkylamines on the structure of rat locomotor activity
34. Quantitative assessment of the microstructure of rat behavior: I. f(d), the extension of the scaling hypothesis
35. Somatodendritic localization of 5-HT1A and preterminal axonal localization of 5-HT1B serotonin receptors in adult rat brain
36. Serotonin1B receptor activation mimics behavioral effects of presynaptic serotonin release
37. Excitatory influence of rat subthalamic nucleus to substantia nigra pars reticulata and the pallidal complex: Electrophysiological data
38. Activation of subthalamic neurons produces NMDA receptor-mediated dendritic dopamine release in substantia nigra pars reticulata: A microdialysis study in the rat
39. Differential sensitivity of 5-HT1B auto and heteroreceptors
40. A direct comparison of amphetamine-induced behaviours and regional brain dopamine release in the rat using intracerebral dialysis
41. The output neurones and the dopaminergic neurones of the substantia nigra receive a GABA-containing input from the globus pallidus in the rat
42. Neurons of the subthalamic nucleus in primates display glutamate but not GABA immunoreactivity
43. Responses of hippocampal pyramidal cells to putative serotonin 5-HT1A and 5-HT1B agonists: A comparative study with dorsal raphe neurons
44. Pharmacological analysis of the behavioural and thermoregulatory effects of the putative 5-HT1 receptor agonist, RU 24969, in the rat
45. Single subthalamic nucleus neurons project to both the globus pallidus and substantia nigra in rat
46. 5-HT2 mediation of acute behavioral effects of hallucinogens in rats