Inhibition of telomerase in tumor cells by ribozyme targeting telomerase RNA component

Science in China, Series C: Life Sciences

Volumn 45, Issue 1, 2002, Pages 87-95

  Liu, Bailin ^a   Qu, Yi ^a   Liu, Shuqiu ^a   Ouyang, Xuesong ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Cleavage; HeLa cells; Inhibition; Ribozyme; Telomerase

Indexed keywords

CELLS; DRUG PRODUCTS; RNA; TRANSPLANTATION (SURGICAL); TUMORS;

APOPTOSIS;

ENZYMES;

EUKARYOTA; MUS MUSCULUS;

EID: 0036118738     PISSN: 10069305     EISSN: None     Source Type: Journal    
DOI: 10.1360/02yc9010     Document Type: Article

References (13)

1. The telomerase terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity
2. The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
3. The RNA component of human telomerase
4. Specific association of human telomerase activity with immortal cell and cancer
5. Telomere length predicts replicative capacity of human fibroblasts
6. Telomeres, telomerase and cancer
7. Resistance to apopotosis in human cell conferred by telomerase function and telomere stability
8. Role of telomerase in cellular proliferation and cancer
9. Is small cell lung cancer the perfect target for antitelomerase treatment?
10. Antisense telomerase treatment induction of two distinct pathways of apoptosis and differentiation
11. Quantitative and qualitative detection of cell telomerase
12. Repression of the telomerase catalytic subunit by a gene on human chromosome 3 that induces cellular senescence
13. Suppression of telomerase reverse transcriptase (hTERT) expression of differentiated HL-60 cells: Regulatory mechanisms