Effect of imipramine on brain D-1 and 5-HT-2A receptors in a chronic unpredictable stress model in rats

Polish Journal of Pharmacology

Volumn 54, Issue 2, 2002, Pages 89-93

  Ossowska, Grazyna ^a   Nowak, Gabriel ^a   Klenk Majewska, Bozena ^a   Danilczuk, Zofia ^a   Zebrowska Łupina, Iwona ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

5 HT 2A receptors; Brain; Chronic stress; D 1; Imipramine; Rats

Indexed keywords

ANTIDEPRESSANT AGENT; BRAIN RECEPTOR; DOPAMINE 1 RECEPTOR; IMIPRAMINE; RADIOLIGAND; SEROTONIN 2A RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CHRONICITY; CONTROLLED STUDY; DEPRESSION; DRUG MECHANISM; LIGAND BINDING; LIMBIC SYSTEM; MALE; NONHUMAN; PATHOPHYSIOLOGY; RAT; RECEPTOR DENSITY; STRESS;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BEHAVIOR, ANIMAL; CHRONIC DISEASE; DEPRESSION; DISEASE MODELS, ANIMAL; IMIPRAMINE; MALE; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, DOPAMINE D1; RECEPTORS, SEROTONIN; STRESS, PSYCHOLOGICAL;

EID: 0036113126     PISSN: 12306002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Autoradiographic demonstration of increased serotonin and beta-adrenergic receptor binding sites in the brain of suicide victims
2. 2 binding sites in the frontal cortex and control subjects
3. 3H-LSD) in the blood platelets of depressed patients
4. 1C receptor-mediated behaviour in rats following chronic treatment with 5-HT receptor agonists, antagonists or anti-depressants
5. 2 receptor binding on blood platelets; a peripheral marker for depression?
6. Dopamine and depression
7. 2 receptors in chronic fluoxetine-treated rats
8. A role for 5-HT in the action of antidepressant drugs
9. 1 receptor agonists in the behavioural despair animal model of depression
10. Blunting of reactivity of DA transmission to palatable food: A biochemical marker of anhedonia in the CMS model?
11. 2 dopamine receptors in the rat brain
12. Changes in dopamine receptor mRNA expression following chronic mild stress and chronic antidepressant treatment
13. Dopamine receptors in the striatum of rats exposed to repeated restraint stress and alprazolam treatment
14. The revised monoamine theory of depression: A modulatory role for monoamines, based on new findings from monoamine depletion experiments in humans
15. Acute and chronic stress effects on open field activity in the rat: Implications for a model of depression
16. Animal model of depresion: Tests of three structurally and pharmacologically novel antidepressant compounds
17. The effects of stressful life events on depression
18. 3H] SCH 23390 binding sites in the rat striatum and limbic system
19. 2 agonists
20. 2 receptor-mediated behavior 11 days after shock in learned helplessness rats
21. 1 receptors by chronic imipramine is species specific
22. Reversal of stress-induced deficit in aggression by monoamine oxidase inhibitors
23. Acute effect of dopamine agonists and some antidepressants in stress-induced deficit of fighting behavior
24. Brain monoamine receptors in a chronic unpredictable stress model in rats
25. Platelet serotonin-2 receptor binding sites in depression and suicide
26. Effects of imipramine on serotoninergic and beta-adrenergic receptor binding in a realistic animal model of depression
27. 2 receptor binding in limbic forebrain associated with chronic mild stress-induced anhedonia and its reversal by imipramine
28. Pharmacological validation of the chronic mild stress model of depression
29. Serotonin neuroscience discoveries usher in a new era of novel drug therapies for psychiatry
30. 1A receptors and pharmacotherapy
31. Chronic antidepressant therapy and associated changes in central monoaminergic receptor functioning
32. Effects of psychotropic drugs on the behavior and neurochemistry of olfactory bulbectomized rats
33. 2 receptors and transport sites for serotonin
34. Animal models of depressions, an overview
35. Changes in mesolimbic dopamine may explain stress-induced anhedonia
36. Chronic mild stress-induced anhedonia: A realistic animal model of depression
37. Neuropsychological profile linked to low dopamine: In Alzheimer's disease, major depression and Parkinson's disease
38. 5HT2 receptor changes in major depression
39. Chronic stress reduces fighting behavior of rats: The effect of antidepressants
40. The influence of antidepressants on aggressive behavior in stressed rats: The role of dopamine